For a patient with a rising PSA after prostatectomy with seminal vesicles being negative for disease at surgery, do you ever treat the prostate bed and seminal vesicle bed with different doses in an SIB plan?

For example, the prostate bed/bladder neck receives 70 Gy and the seminal vesicle bed receives 60 Gy? Based on current randomized trials, what dose of XRT do you use for salvage therapy?

Answer from: Radiation Oncologist at Academic Institution

Conclusion: The short answer is no, I do not utilize de-escalation to the SV bed, and I treat the entire operative bed to 64-66.6Gy. Below is a rationale and some linked resources, if helpful: A. Dose: The recently published RTOG 0534 allowed a range of doses (64.8Gy-70.2 Gy); however, sin...

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For a patient with a rising PSA after prostatectomy with seminal vesicles being negative for disease at surgery, do you ever treat the prostate bed and seminal vesicle bed with different doses in an SIB plan?

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