Can PRRT be used in a patient with a GI neuroendocrine tumor and estimated GFR of less than 30?  

Unfortunately there is no safety data for the use of PRRT in patients with GFR <30 ml/min. A creatinine clearance <50 ml/min is listed only as a relative contraindication by NANETS/SNMI (Hope et al 2020) and ENETS guidelines (Hicks et al 2017). Based on over 2 decades of experience with PRRT, ...