How would you treat an older patient with multiple co-morbidities and borderline performance status with resectable esophageal cancer in light of ESOPEC trial?

This is a great question. There is lacking data to answer your question, so you are getting my professional opinion and that which I heard discussed at the recent Best of ASCO by Binaytara. The simple answer: yes.

We as oncologists need to know the data, know what is "optimal" and individualize for...