Would you offer inguinal nodal RT to a patient with anal SCC (pT1N1a, + inguinal node) following APR in the setting of prior prostate + pelvic nodal radiation?  

Inguinal lymph node dissection is not typically part of APR procedures. Even when surgical dissection of the inguinal lymph nodes is performed, the recurrence or failure rates in this region can still be significant, with some studies reporting failure rates of around 10-15% despite extensive surger...

Yes. I’ve seen an inguinal node recurrence in a patient whose 5 mm anal canal carcinoma was discovered incidentally in a hemorrhoidectomy specimen. I just treated the anus and pelvic lymph nodes and not the inguinal lymph nodes, based on the 2001 update from Jean Papillion and the rest of the ...