In patients with T1 anal squamous cell cancer status post local excision with a close margin, would you recommend close observation or adjuvant concurrent chemoradiation?

Margin is less than 1 mm. Would the grade of the tumor affect your decision? Would any other factors go into your decision?

Answer from: Medical Oncologist at Academic Institution

I would solicit the opinions of my colorectal surgery and GI colleagues to see if re-resection (with TAMIS, for example) is possible. If it is not, I would likely observe. If the margin was positive and not just close, I would do traditional chemoradiation.

Comments

Medical Oncologist at Bhanu Vakkalanka, MD, MBBS
Thank you, Dr. @LoConte. Appreciate the input.

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In patients with T1 anal squamous cell cancer status post local excision with a close margin, would you recommend close observation or adjuvant concurrent chemoradiation?

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