Allergy & Immunology

Mast Cell Disorders

Questions discussed in this category

Is there any role for immunosuppressive/immunomodulatory therapy used off label for mast cell activation syndrome besides omalizumab?

1 Answer available

Are you requiring markers other than LTE4 to be elevated to diagnose MCAS?

There has been new data to suggest LTE4 is not the best urinary marker of mast cell activation, so are you requiring other markers to be elevated to d...

1 Answer available

Do you favor 24 hour urinary metabolites over random urine collection when screening for MCAS?

1 Answer available

Do you diagnose MCAS if a patient is concurrently on drugs known to cause non-specific mast cell degranulation?

1 Answer available

How would you work up a patient with cutaneous mastocytosis?

Is a BM biopsy a must when there is skin involvement? If tryptase level is mildly elevated but less than 20 would you recommend a BM biopsy?

1 Answer available

Papers discussed in this category

Eur J Dermatol,

Telangiectasia macularis eruptiva perstans: a neglected type of mastocytosis with exclusively cutaneous involvement? A case series.

The journal of allergy and clinical immunology. In practice, 2022 Mar 26

Nontryptase Urinary and Hematologic Biomarkers of Mast Cell Expansion and Mast Cell Activation: Status 2022.

The journal of allergy and clinical immunology. In practice, 2022 Mar 25

Personalized Management Strategies in Mast Cell Disorders: ECNM-AIM User's Guide for Daily Clinical Practice.

Allergy & Immunology

Mast Cell Disorders

Questions discussed in this category

Papers discussed in this category

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