General Internal Medicine

Uveitis and Ocular Immunology

Questions discussed in this category

Is it safe to continue azathioprine in a patient with severe bilateral panuveitis (thought to be related to sarcoidosis) and benign ethnic neutropenia, given worsening neutropenia since starting the medication, or should an alternative immunosuppressive agent be considered?

Patient with a history of presumed benign ethnic neutropenia: PMN 1.5 prior to azathioprine and 1.2 after starting. The patient has an intolerance to ...

3 Answers available

Do you continue TNF inhibitors in patients with a new diagnosis of CLL?

Patient with long standing history of HLAB27 associated uveitis on adalimumab and new diagnosis of CLL.

1 Answer available

How would you approach management of nodular scleritis in the setting of suspected GCA?

Can nodular scleritis be a presenting manifestation of GCA?

1 Answer available

Does a low serofast RPR titer (such as 1:1 or 1:2) in the setting of a remote history of appropriately treated latent syphilis in a patient with now uveitis of yet unknown etiology referred from ophthalmology for possible ocular syphilis make a diagnosis of ocular syphilis less likely?

What is your approach to guiding ophthalmologists regarding our clinical suspicion for ocular syphilis and does the quantification of the titer help i...

1 Answer available

How do you approach tapering immunosuppression in a patient with a history of Susac Syndrome who has stabilized on MMF and IVIG?

1 Answer available

How would you approach management of incidentally identified unilateral retinal vasculitis with subsequent labs revealing +P-ANCA?

Patient is asymptomatic. Labs showed +P-ANCA 1:160. Negative MPO and PR3.

2 Answers available

What is your approach to the workup for an underlying systemic condition in a patient presenting with retinal vasculitis?

1 Answer available

What is your approach to evaluation of underlying autoimmune disease in patients with bilateral scleromalacia?

1 Answer available

How do you diagnose and treat patients who develop uveitis while on bisphosphonate therapy for osteoporosis?

Are there specific features that suggest drug-induced uveitis versus de novo uveitis?

1 Answer available

What are the benefits of sending HLA B27 genotype over HLA B27 antigen when evaluating for spondyloarthritis?

2 Answers available

Papers discussed in this category

Curr Rheumatol Rep,

Polymorphism of HLA-B27: 105 subtypes currently known.

Ann Rheum Dis, 2011 Jul 28

HLA-B27 positive patients differ from HLA-B27 negative patients in clinical presentation and imaging: results from the DESIR cohort of patients with recent onset axial spondyloarthritis.

Curr Opin Rheumatol,

Retinal vasculitis.

Journal of ophthalmic inflammation and infection, 2015-12

Clinical and laboratory characteristics of ocular syphilis: a new face in the era of HIV co-infection.

JAMA ophthalmology, 2024 Jan 01

Rising Incidence of Syphilitic Uveitis-Related Hospitalizations in the US.

Investigative ophthalmology & visual science, 2016 Feb

Clinical Manifestations and Outcome of Syphilitic Uveitis.

Cureus, 2020 Jul 07

Biologic Therapies in Sarcoidosis and Uveitis: A Review.

Seminars in arthritis and rheumatism, 2015 May 21

Anti-TNF-α therapy in refractory uveitis associated with sarcoidosis: Multicenter study of 17 patients.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2011 Nov 27

Adalimumab successful in sarcoidosis patients with refractory chronic non-infectious uveitis.

General Internal Medicine

Uveitis and Ocular Immunology

Questions discussed in this category

Papers discussed in this category

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