How would you approach management of incidentally identified unilateral retinal vasculitis with subsequent labs revealing +P-ANCA?  

This anecdote raises at least 3 fascinating questions. First, how do you approach asymptomatic retinal vasculitis? Often a retinal vasculitis is defined by the dye, fluorescein, leaking from a retinal vessel on a study called a fluorescein angiogram. By this definition, pedal edema would be a pedal ...

@James Rosenbaum: thanks for your well-thought-out answer. Question (for us non-eye expert rheumys): What factors increase the risk for progression and vision loss in someone with asx retinal vasculitis? I care for many systemic lupus patients (many SLE patients are also p-ANCA positive), and we do...