General Rheumatology

Questions discussed in this category

Are there any clinical trials underway to study additional therapies?

How would you approach management of a patient with longstanding history of SLE, but having active psoriasis?

SLE manifestations include arthralgias and cytopenias which are stable. Previously did well on methotrexate, but developed GI side effects. HCQ is on ...

3 Answers available

What are some important considerations for use of ACE inhibition in scleroderma renal crisis patients who require dialysis?

For example, is captopril dialyzable?

1 Answer available

Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?

2 Answers available

Do you routinely consider FDG PET/CT imaging for workup of fever of unknown origin?

1 Answer available

Can Dupixent (dupliumab) be safely used in patients who are taking other biologics for rheumatic disease?

1 Answer available

What is your approach to differentiating RA-ILD from medication toxicity (I.e. from methotrexate)?

1 Answer available

Is there a benefit to having a transition period in which a patient continues following with their previous pediatric rheumatologist while establishing care with a new adult rheumatologist?

What do adult rheumatologists need to understand about pediatric diseases?

3 Answers available

How do you approach evaluation and management of a patient with recurrent monoarticular inflammatory arthritis of unclear etiology?

Synovial fluid analysis: cell count >100,000, > 80% neutrophils. Gram stain, cultures (including fungal and mycobacterial), synovial biopsy, and...

2 Answers available

How do you counsel patients who experience diarrhea from mycophenolate mofetil (Cellcept)?

Do you generally recommend anti-diarrheals, dietary modifications, or consider this an unacceptable side effect and move to other therapies?

2 Answers available

Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?

4 Answers available

What is your workup and treatment approach for cranial neuropathies in patients with lupus?

1 Answer available

For patients with SLE, is there an ANC level for which you would hold or adjust hydroxychloroquine in an asymptomatic patient?

UpToDate recommends Hydroxychloroquine for all SLE patients, but neutropenia is sometimes ascribed to HCQ rather than the underlying disease. What lev...

2 Answers available

How long do you maintain patients with anti-synthetase syndrome on Rituximab?

The patient was treated with two doses of Rituximab and on MMF. Now with stable lung function and normalized CK.

2 Answers available

What would be the preferred treatment option for PMR if patient develops gastric perforation soon after initiation of steroids?

1 Answer available

How would you approach management of nodular scleritis in the setting of suspected GCA?

Can nodular scleritis be a presenting manifestation of GCA?

1 Answer available

How long do you treat retroperitoneal fibrosis with immunosuppression?

What imaging do you use to monitor disease activity? Imaging only shows chronic, fibrotic lesions making it hard to assess disease activity.

1 Answer available

What are some of the biggest challenges you run into when patients transition from pediatric to adult care?

1 Answer available

Should the age at which patients transition from pediatric to adult care differ depending on the disease diagnosis?

What nuances do adult rheumatologists need to understand about pediatric diseases?

2 Answers available

Do you recommend adjusted adult cancer screening for patients who have been on long term biologics and/or tsDMARDs since childhood?

1 Answer available

How would you approach management of a patient with ESRD on the transplant list who is found to have high titer APS labs (ACL, B2GP1, LAC)?

1 Answer available

What are some strategies to help teach patients transitioning from pediatric to adult care to become more independent with respect to their care and less dependent on their caregivers?

1 Answer available

How do you discuss sexual health with pediatric patients transitioning to adult rheumatology care when the patient is accompanied by parents or caregiver?

1 Answer available

In a patient with low titer +anti-SAE antibody and known ILD, but no other clinical features of dermatomyositis, how would you approach further testing or would you treat the patient as dermatomyositis associated ILD?

1 Answer available

How often do you see bony erosions in patients with Lyme arthritis?

1 Answer available

What is your treatment approach for a young female who has an idiopathic small right elbow effusion with synovial thickening that has resulted in limitation in her range of motion?

1 Answer available

What is your approach to monitoring patients referred for high titer +RF and +CCP but without active symptoms of inflammatory arthritis?

X-rays without inflammatory changes. RF >120, CCP >250

2 Answers available

How do you approach a patient on anti-TNF with positive Quantiferon (previously negative) with negative chest x-ray and no symptoms?

7 Answers available

How do you approach use of DMARDs and/or biologics for inflammatory arthritis in patients with a history of seizure disorder on anti-epileptic medications?

Is there any concern for drug interactions of DMARDs and/or biologics with anti seizure medications?

1 Answer available

When would you consider using G-CSF in patients with rheumatic disease who have received cyclophosphamide?

2 Answers available

Do you perform genetic testing when patients have persistent hypogammaglobulinemia after rituximab therapy?

2 Answers available

Are there any concerns with live vaccine innoculation and patients who are on denosumab?

1 Answer available

How do you approach medication management in patients with RA when transitioning from csDMARD triple therapy to anti-TNF?

Which csDMARD do you taper in order, and is there a tapering strategy (duration/dose)?

2 Answers available

Are you comfortable with using NSAIDs in a patient on methotrexate for inflammatory arthritis?

Given the drug-drug interaction, do you monitor more closely for methotrexate toxicity, counsel on symptoms of methotrexate toxicity, or avoid the com...

2 Answers available

What is your approach to DVT prophylaxis in patients who require IVIG but are at increased risk for thrombotic events?

E.g., a patient with newly diagnosed CIDP who is wheelchair-bound.

2 Answers available

How do you approach managing nausea and GI side effects when initiating methotrexate?

2 Answers available

What is your approach to management of hyperlipidemia in patients taking JAK inhibitors?

1 Answer available

How would you approach management of a young male patient with discoid lupus who has had minimal response to hydroxychloroquine (and subtherapeutic whole blood levels) who continues to use tobacco products?

2 Answers available

Do you combine methotrexate and leflunomide for the treatment of RA?

3 Answers available

How do you manage a patient with cervical cancer who has FDG uptake in bilateral ischial tuberosities with lytic areas on CT correlate, and also has a history suspicious for untreated polymyalgia rheumatica with chronic symptoms in the same anatomic locations?

Cervical cancer FIGO stage IIIC2. Bloodwork shows elevated ESR and CRP.

4 Answers available

What is the maximum dose of leucovorin that you use with methotrexate?

2 Answers available

Do you continue methotrexate in patients with inflammatory arthritis who develop non-melanomatous skin cancer while on therapy?

1 Answer available

In patients with sicca symptoms and positive SSA/SSB how often do you perform other diagnostic testing such as salivary gland ultrasound, biopsy, Shirmers, ocular staining, stimulated salivary flow, etc?

Is the diagnosis of Sjogren's mostly clinical in a patient with a consistent history and physical with positive serologies?

2 Answers available

How do you approach a patient with elevated bone specific ALP (>2X the normal limit), but no other evidence of Paget's disease?

Normal Vitamin D, bone scan showed osteoarthritis

1 Answer available

Is there a role for the use of transient elastography (FibroScan) to monitor liver fibrosis in patients on long term methotrexate?

3 Answers available

What is the typical timeline for remission of autoimmune hypoglycemia?

1 Answer available

How would you manage cardiac sarcoid with intolerance/contraindications to methotrexate, azathioprine, and mycophenolate/mycophenolic acid and that has proven refractory to adalimumab and infliximab as determined by PET?

2 Answers available

Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?

1 Answer available

Would you switch azathioprine to a different immunosuppressant if a controlled patient with SLE develops melanoma and/or non-melanoma skin cancer?

2 Answers available

When considering a biologic for seropositive RA after failure of methotrexate or triple therapy, do you consider using abatacept as a first line biologic or would prefer choosing TNFi?

2 Answers available

In a patient with isolated HLA B27+ anterior uveitis, how long would you continue immunosuppressive therapy?

The patient has no extraocular features of a spondyloarthropathy and is on methotrexate. No active eye disease for past 1 year.

1 Answer available

Do you avoid hyaluronic acid injections in patients with chondrocalcinosis on imaging?

2 Answers available

How do you approach the work up of pulmonary artery aneurysm in the absence of other clinical features of Behcet’s?

1 Answer available

Do you find HZV titers useful in diagnosing shingles sine herpete?

1 Answer available

How would you approach management of a patient with checkpoint inhibitor induced psoriatic arthritis?

Pt with active skin and joint disease. Previously on Cemiplimab (PD-1) for squamous cell carcinoma of the skin. Do you avoid traditional DMARDs due to...

1 Answer available

What is your approach to differentiating tender spots (as in fibromyalgia) and enthesitis (as in axSpA)?

1 Answer available

What is your approach to work up for patients referred for early onset osteoarthritis?

1 Answer available

How do you approach work up for underlying rheumatologic disease in patients referred for chronic urticaria?

2 Answers available

When would you consider utilizing bone scintigraphy in the assessment of inflammatory arthritis?

2 Answers available

How are you utilizing vibratory devices for reducing pain associated with injection or procedures?

In which situations or patient populations do you find this useful? How is it sterilized?

3 Answers available

How do you approach treatment of a patient with active RA and a history of Lynch Syndrome?

Does your choice of DMARD/biologics change due to increased risk of malignancy?

1 Answer available

How do you utilize cytokine panels in your clinical practice?

Is there utility when classic inflammatory markers (ESR,CRP) or disease specific markers (C3, C4, dsDNA) do not correlate with patients disease activi...

1 Answer available

What is your approach to evaluation and management of a patient with Blau Syndrome and GI manifestations?

2 Answers available

How do you approach management of Adult Onset Still's disease in a patient with ongoing fatigue and inflammatory joint pain despite methotrexate, colchicine, canakinumab and tocilizumab?

Heritable autoinflammatory gene testing negative. Is there a role for TNF inhibitor?

3 Answers available

How do you decide when to obtain genetic testing for suspected autoinflammatory conditions in adults?

2 Answers available

How do you approach hypocomplementemia in Sjogren’s without features of lymphoma?

3 Answers available

Is there a risk of hepatitis C activation with rituximab in a patient who has a history of HCV treated with antivirals and who is in sustained viral response?

1 Answer available

Do you recommend sending an autoimmune work up for patients with recurrent nephrolithiasis and 24 hour urine chemistries consistent with distal renal tubular acidosis?

1 Answer available

Do you prefer celecoxib over a nonselective NSAID in patients with chronic kidney disease?

4 Answers available

What is your approach to counseling patients regarding re-initiation of anti-TNF therapy after completion of treatment for non-disseminated pulmonary histoplasmosis?

Would it be safe to resume and if so, when?

2 Answers available

For how long do you recommend treatment for latent tuberculosis prior to initiation of anti-TNF therapy?

6 Answers available

How do you monitor patients with incidentally found high titer anti-smooth muscle antibodies without stigmata of liver disease?

3 Answers available

How do you approach evaluation for underlying rheumatologic disease in patients with chronic asymptomatic thrombocytopenia?

Thrombocytopenia is moderate (80-100,000 microL). No concomitant cytopenias present.

2 Answers available

How do you approach management of adult patients with CVID and sarcoid-like syndrome?

1 Answer available

What is your approach to differentiating and managing DMARD-induced nodulosis (induced by methotrexate or leflunomide for example) from "de novo" RA nodules in seropositive RA patients?

1 Answer available

Do you restrict topical diclofenac use in your patients with chronic kidney disease?

3 Answers available

How do you approach patients referred for C1-2 pannus/erosions without clinical findings or serologies consistent with RA or CPPD arthropathy?

3 Answers available

Does your institution have formal policies or work flows to reduce unnecessary IGRAs ordered for patients on biologics?

1 Answer available

What do you recommend to patients when they are having an acute flare of fibromyalgia symptoms?

1 Answer available

What is your approach to monitoring for hepatic fibrosis in chronic methotrexate use?

Do you frequently order liver biopsies for these patients?This question is part of a collaboration with RheumMadness and is specifically in reference ...

2 Answers available

What isolation policies are Rheumatology offices employing for both staff and patients diagnosed with COVID-19 given the new CDC guidelines?

CDC Healthcare Guidance CDC Isolation and Work Restriction Guidance CDC Immunocompromised Guidance

1 Answer available

Is there utility in monitoring IgE levels in patients with IgG4-RD?

1 Answer available

Do you recommend Vitamin D and omega 3 fatty acid supplementation for prevention of autoimmune disease?

This question is part of a collaboration with RheumMadness and is specifically in reference to: Prevention of Autoimmune Disease: Vitamin D and O...

2 Answers available

What characteristics make a PMR patient a good candidate for sarilumab?

Do you plan to use sarilumab for all patients with relapsing or refractory PMR or are there certain features that will make you more or less likely to...

3 Answers available

How do you counsel and manage joint pain after isotretinoin treatment?

1 Answer available

What is your approach to a patient with IgG4RD with past pulmonary involvement (biopsy proven) managed with steroids alone, now with new hematuria/proteinuria, but stable renal function?

Would you obtain renal biopsy first or treat with additional immunosuppression for suspected renal involvement related to IgG4?

4 Answers available

How do you counsel patients on the use of topical nitroglycerin for Raynaud's?

What formulation of topical nitroglycerin do you use?

1 Answer available

How do you approach biologic initiation in patients with inflammatory arthritis and repeatedly indeterminate Quantiferon?

5 Answers available

How do you approach ongoing screening for TB in patients with a history of treated latent TB, but who have ongoing use of DMARDs and/or biologics given Quantiferon testing and PPD can remain positive?

How do you approach ongoing screening for TB in patients with history of treated latent TB, but have ongoing use of DMARDs and/or biologics given quan...

1 Answer available

Would you feel comfortable adding benlysta to patient already taking both mycophenolate and tacrolimus (and hydroxychloroquine) who still has some evidence of active lupus nephritis?

3 Answers available

What is your approach to working up diarrhea in an immunocompromised patient?

1 Answer available

Do you typically adjust or hold immunosuppression in a well-controlled RA patient who is being treated for Mycobacterium avium-intracellulare (MAI)?

1 Answer available

Do you avoid the use of hydroxychloroquine in patients with psoriasis and/or psoriatic arthritis?

1 Answer available

Do you have concerns with the use of oral contraceptives in patients on JAK inhibitors given the black box warning for thromboembolic events?

How has this impacted your counseling and management?

2 Answers available

What would be your approach to a patient with Scleroderma/Myositis overlap syndrome (+anti-Ku) and active inflammatory eye disease despite high dose mycophenolate?

2 Answers available

What else do you consider in the differential diagnosis for pulmonary-renal syndromes if there is low clinical and serologic evidence of AAV, Goodpasture's or other rheumatologic disease (SLE, RA, APS, Scleroderma)?

2 Answers available

Do you utilize post-vaccination IgG titers to detect common variable immunodeficiency in patients who are about to start or are actively on B cell depleting therapy?

2 Answers available

Do you counsel your patients on the potential decreased effectiveness of oral contraceptives while on Sarilumab?

If so, do you routinely recommend use of an additional form of contraception?

1 Answer available

How do you approach GI prophylaxis (e.g., PPIs, H2 blockers) in patients on long-term NSAIDs?

1 Answer available

How do you manage a patient with severe RA or SLE that worsens after stopping immunosuppressants due to having chronic foot ulceration?

2 Answers available

At what point do you consider a patient to have relapsing PMR?

How much cumulative prednisone exposure do you tolerate and how many attempts at tapering will you pursue before considering addition of a steroid spa...

4 Answers available

How do you approach follow up of young patients with isolated +ANA, but no current clinical signs or symptoms of SLE?

This question is part of a collaboration with RheumMadness and is specifically in reference to: Antibodies Before SLE.

6 Answers available

Do you typically screen patients for antiphospholipid antibodies in autoimmune diseases besides lupus in the absence of a clotting event?

6 Answers available

Do you consider anti-viral prophylaxis in patients taking JAK inhibitors who have recurrent uncomplicated Zoster infection, but would prefer not changing therapy?

2 Answers available

How do you approach management of a patient with persistent EBV infection and MAS despite treatment with Rituximab, anakinra and canakinumab?

Would you consider alternative B cell depleting therapies such as ofatumumab or ocrelizumab?

1 Answer available

Does hepatitis B vaccination reduce the risk of HBV reactivation associated with immunosuppressive therapy?

For example, in patients who are HbSAg negative, anti-HBc positive and HbSAb negative, does vaccination reduce reactivation risk?

2 Answers available

How do you approach a negative ANA and positive dsDNA in patients with arthralgia, hair loss, or other UCTD features?

5 Answers available

Would a surgical decompression be indicated in a patient with amyloidosis and severe median neuropathy at the wrist?

1 Answer available

How do you approach management of a patient with idiopathic PAH and +ANA, but no other current symptoms/signs of active rheumatologic disease?

3 Answers available

Is it safe to combine mycophenolate and adalimumab for management of pulmonary sarcoidosis in a patient that could not tolerate methotrexate?

3 Answers available

How would you approach treatment of active inflammatory arthritis in a patient with MCTD (+RNP/+Chromatin) and stable ILD who has failed MMF, azathioprine and methotrexate?

Would you consider belimumab over a TNF inhibitor for inflammatory arthritis? Which agent would be more beneficial for the lung disease?

2 Answers available

At what point would you consider anticoagulation in a pregnant patient with lupus nephritis and non-nephrotic range proteinuria?

3 Answers available

How do you approach immunosuppression in patients with a positive Interferon Gamma Release Assay and prior intravesicular BCG treatment for bladder cancer?

Assuming no symptoms of TB, should patients be treated for latent TB prior to starting TNF inhibitors or other immunosuppressive agents?

1 Answer available

What treatment options do you recommend in a patient with idiopathic granulomatous mastitis that has not improved on steroids and methotrexate?

1 Answer available

Does IVIG or subcutaneous Ig interfere with monoclonal antibody therapy (i.e. dupilumab, infliximab, rituximab, etc)?

How should IVIG and either biologic injections or infusions be spaced?

2 Answers available

How will you approach tapering sarilumab in patients with PMR in remission?

After what interval of sustained remission will you attempt to taper, and will you do so by first widening the dosing interval?

2 Answers available

What are your top takeaways from ACR Convergence 2023?

2 Answers available

Do you have a preference between Quantiferon Gold and T-spot TB for screening in patients starting immunosuppressive agents?

1 Answer available

What is your approach to evaluation in patients who present with erythromelalgia?

1 Answer available

How will you approach drug sequencing in patients with PMR given the SAPHYR data?

Will you initiate sarilumab as a first steroid sparing agent or will you still pursue a DMARD such as methotrexate before initiating sarilumab? To wha...

2 Answers available

How will you adjust your approach to steroid taper in patients with PMR also on sarilumab?

2 Answers available

What baseline and ongoing testing do you recommend for patients with PMR who are going to be on a prolonged steroid taper?

Do you universally perform baseline DEXA and Hgb A1C? How often are you obtaining routine labs?

2 Answers available

How do you differentiate active vasculitis from pregnancy complications such as pre-eclampsia and HELLP in a patient with AAV?

3 Answers available

How do you approach the timing of Rituximab during pregnancy in a patient with life or organ threatening autoimmune disease?

3 Answers available

Is there a concern for the potential of future congenital malformations in offspring when preservation of eggs and sperm is done AFTER cyclophosphamide treatment given that it is an alkylating agent?

1 Answer available

In patients taking biologics who are planning joint replacement and are known MRSA carriers do you perform decolonization prior to surgery?

0 Answers available

Can joint replacement surgery be performed in someone with active Paget’s disease elsewhere?

1 Answer available

Do you stop TNF inhibitors during the third trimester of pregnancy?

2 Answers available

What is your approach to patients with severe sicca symptoms and history of B Cell lymphoma?

Patient has received treatment with Rituximab and is taking hydroxychloroquine.

1 Answer available

What is your approach to tapering chronic steroids in patients who are at high risk of HPA suppression?

For example, patients who have been maintained on 5mg of prednisone for years without previous tapering attempts and the rheumatic disease is not acti...

1 Answer available

How do you approach pre-conception counseling in males who are on medications for which there is limited or no data such as Jak inhibitors, apremilast, or belimumab?

2 Answers available

Do you hold rituximab for cataract surgery?

If so, when do you recommend timing for the cataract surgery?

3 Answers available

How would approach the management of a patient with significantly positive anticardiolopin and beta 2 glycoprotein antibodies in the absence of any clotting (including obstetric) history but with significant thrombocytopenia (but no other features of active connective tissue disease)?

1 Answer available

How do you approach evaluation and management of arthralgia in a patient after CAR-T cell therapy?

1 Answer available

Have you seen drug induced SCLE from IL-17 inhibitors?

And if so, what is your approach to the diagnosis?

1 Answer available

How would you approach management of incidentally identified unilateral retinal vasculitis with subsequent labs revealing +P-ANCA?

Patient is asymptomatic. Labs showed +P-ANCA 1:160. Negative MPO and PR3.

2 Answers available

Is polymyalgia rheumatica associated with increased toxicity for lung SBRT?

1 Answer available

If a patient with relapsing remitting MS has comorbid Sjogren's syndrome and is on hydroxychloroquine (Plaquenil), how does that impact choice of DMT for MS?

1 Answer available

In a patient with active spondylarthritis and uveitis who cannot take TNF inhibitors, what is your next agent of choice?

1 Answer available

Would you consider a biologic or JAK inhibitor to manage active PsA in a patient on chronic antibiotic therapy if they had previously failed all conventional DMARDs (including apremilast)?

Patient is on antibiotics for chronic spinal hardware infection.

1 Answer available

What is your approach to continuing or altering therapy when inheriting a patient with combined biologic immunosuppression that is in excess of guidelines?

How do you approach de-escalation or justify therapy maintenance? Do you have tiers of medications that you attempt to de-escalate first? In one parti...

1 Answer available

Would you have a patient temporarily discontinue methotrexate while receiving a FAST or FAST FORWARD regimen for breast irradiation?

The patient is on a dose of 22 mg of methotrexate weekly for severe rheumatoid arthritis. If you would discontinue the methotrexate, how long would y...

1 Answer available

What is your approach to management of chronic neutropenia in a patient with Sjogren’s who was recently diagnosed with metastatic endometrial cancer and plans to start chemotherapy?

ANC <500

1 Answer available

How do you manage patients with systemic sclerosis and chronic thrombotic microangiopathy on renal biopsy, but no other evidence of scleroderma renal crisis?

Patient with nephrotic range proteinuria, but there is no evidence of active TMA on renal biopsy.

1 Answer available

Do you find MRI helpful to differentiate early erosive OA from psoriatic arthritis when early X-ray changes in both conditions may be hard to distinguish?

1 Answer available

What is your approach to management of elevated liver enzymes in patients who recently started treatment with tocilizumab?

1 Answer available

How do you approach dosing of anakinra in MAS?

1 Answer available

What is your approach to evaluating a patient with known rheumatologic disease and elevated free kappa:lambda ratio, but no evidence of monoclonal immunoglobulins?

1 Answer available

What is your approach to rheumatologic disease management during the current methotrexate shortage?

2 Answers available

How long would you wait to start another biologic agent after Rituximab administration in patients with dermatomyositis and refractory inflammatory arthritis (intolerant to traditional DMARDs)?

Patient with dermatomyositis on rituximab with refractory inflammatory arthritis. Intolerant of traditional DMARDs such as methotrexate, leflunomide, ...

1 Answer available

Would you consider re-irradiation for recurrence of Dupuytren's Contracture?

It's been 5+ years after the first course. If you decide to re-irradiate what dosing schema would you use?

2 Answers available

Do you use conventional DMARDs aside from methotrexate to prevent anti-drug antibody development for patients on infliximab?

This question is part of a collaboration with RheumMadness and is specifically in reference to: Etanercept + Methotrexate.

3 Answers available

How would you manage tubulointerstitial nephritis and renal tubular acidosis (RTA) in a patient with Sjogren's who is pregnant?

2 Answers available

What is the optimal timing for Zoster vaccine administration for a patient who recently recovered from herpes zoster infection and is now planning to start B-cell depletion therapy?

1 Answer available

What is your approach to elevated CK in patients without clinical or serologic evidence of immune mediated myopathy?

1 Answer available

Does synovial biopsy provide diagnostic value in undifferentiated inflammatory arthritis?

Apart from ruling out malignancy or infection?

1 Answer available

Is there any clinical benefit in referring patients with SLE or Sjogren's with cognitive impairment for neuropsychological testing?

How do you differentiate symptoms related to centralized pain syndrome from possible cognitive dysfunction?

2 Answers available

How do you counsel patients regarding alcohol intake when prescribing DMARDs other than methotrexate?

Such as Leflunomide, Sulfasalazine, Mycophenolate or Azathioprine, since all of these medications have potential to cause liver enzyme elevation and i...

1 Answer available

How do you approach management of patients with active RA and recurrent non-severe C.diff?

(Patient with active RA despite hydroxychloroquine)

1 Answer available

How do you manage injection site reactions in patients on subcutaneous biologics such as TNF inhibitors?

In what cases do you discontinue the medication?

2 Answers available

How long do you expect gastrointestinal side effects of leflunomide to persist after stopping treatment?

2 Answers available

Do you generally recommend starting nintedanib prior to immunosuppressive therapy in a patient with CTD-ILD?

Do you prefer to start with nintedanib and then add immunosuppressive agents, or give a trial of immunosuppressive medication first, then add nintedan...

4 Answers available

What would be the main indications for opting for biosimilars over an original biologic, outside of insurance barriers?

Are there any instances where you would prefer a biosimilar rather than the reference product?

2 Answers available

Would you use TNF inhibitors in patients with features of SLE, but active peripheral and axial spondylarthritis?

Patient with sacroiliitis on imaging, failure of two NSAIDs.

2 Answers available

When tapering moderate to high doses of long term steroids do you routinely monitor for adrenal insufficiency?

Do you attempt to taper fully or maintain at a low dose?

2 Answers available

How do you approach the workup for a patient with persistently elevated inflammatory markers (CRP and ESR) whose history and exam do not point to a clear cause?

4 Answers available

Do you combine oral and topical NSAIDs for pain relief?

2 Answers available

Would you be comfortable using a JAK inhibitor in a patient with baseline thrombocytosis?

Would the etiology of the thrombocytosis play a role in your decision-making?

1 Answer available

What target do you utilize in clinical practice for defining disease remission in RA?

This question is part of a collaboration with RheumMadness and is specifically in reference to:BeSt TrialMeasurement of Patient Outcomes in Arthritis

1 Answer available

Do you recommend chlorhexidine mouth rinse for prophylaxis against oral complications in patients undergoing dental work who are immunosuppressed?

1 Answer available

Would you consider re-challenging a patient with rituximab after they experienced delayed neutropenia?

In a patient for whom rituximab is the best option for their disease management.

2 Answers available

How do you differentiate the normal feeding vessel to the lunate from an erosion or power doppler signal on ultrasound?

1 Answer available

How do you counsel patients about the malignancy risk associated with azathioprine?

1 Answer available

Do you recommend patients continue folic acid for a few weeks after methotrexate discontinuation?

1 Answer available

How do you approach the usage of hydroxychloroquine in patients with rheumatologic conditions and baseline cardiomyopathy or heart failure?

1 Answer available

Do you continue to utilize ESR and CRP in patients on tocilizumab?

2 Answers available

How do you approach the use of hydroxychloroquine in patients with a history of visual field defect from another cause such as macular degeneration or diabetic retinopathy?

3 Answers available

Is there utility in obtaining pericardial fluid autoimmune labs such as ANA or RF in patients with recurrent idiopathic pericardial effusions, but no other clinical or serologic evidence of rheumatic disease?

1 Answer available

How do you approach evaluation of hypocomplementemia in a patient with arthralgias and a history of Hodgkin's lymphoma treated in the past?

ANA and ENA negative

1 Answer available

How do you manage severe Raynaud's phenomenon with ulceration in scleroderma patients that is refractory to oral agents (CCBs, PDEis, ARBs, and ERAs)?

2 Answers available

Is there any role of sympathectomy in Raynaud’s disease?

2 Answers available

How do you approach oral DMARD and/or biologic selection in patients with RA and a history of gastric bypass or whom are planning bariatric surgery?

1 Answer available

How do you counsel patients regarding contraception use while taking mycophenolate/mycophenolic acid?

2 Answers available

Would you consider use of belimumab in a patient with SLE with recurrent anterior uveitis who failed other treatment options?

Patient failed topical ocular therapies, methotrexate, azathioprine.

2 Answers available

In which clinical scenarios is relying on the urine protein-to-creatinine ratio as a measure of proteinuria unreliable, and interpretations should be made looking at urine protein and urine creatinine separately?

1 Answer available

How do you manage a patient with progressive cerebellar ataxia and positive cardiolipin antibodies?

Do you wait 12 weeks for confirmation to begin treatment if patient is declining?

1 Answer available

What is your approach to patients who present with unilateral Raynaud's?

3 Answers available

Do you typically see peripheral neuropathy in patients with castleman syndrome?

2 Answers available

How do you manage a patient with giant cell arteritis treated with weekly tocilizumab and low dose glucocorticoid who develops sudden vision loss?

2 Answers available

Is rituximab for refractory ITP contraindicated in the setting of an active COVID infection, particularly in a patient with asymptomatic COVID?

2 Answers available

What is your approach to the use of NSAIDs in patients with a history of gastric sleeve/bypass?

1 Answer available

How do you interpret elevations in ESR and CRP in the setting of increased BMI?

4 Answers available

When do you consider discontinuing Pegloticase in a patient with tophaceous gout who has had excellent response to therapy?

1 Answer available

What is your approach to patients with PMR on steroids over a prolonged initial course who start to experience weakness concerning for steroid myopathy?

1 Answer available

Do you discontinue or adjust azathioprine when a patient develops elevated MCV after starting it?

When it seems fairly certain that this is a drug effect is it something that can just be monitored or requires a change in approach?

2 Answers available

What is your approach to timing of medications like Rituximab and Cyclophosphamide around plasmapheresis in patients on daily PLEX?

4 Answers available

What is the appropriate management of arthralgias associated with bosutinib?

1 Answer available

How do you approach treatment of RA with methotrexate in a patient with treated Hepatitis C and normal liver function?

1 Answer available

How do you treat celiac disease associated inflammatory arthritis refractory to gluten free diet?

1 Answer available

Would you consider continuing a biologic for difficult to control autoimmune disease in a patient with a recent diagnosis of a surgically curable solid malignancy?

Would you favor the use of any particular biologics over others?

1 Answer available

Are there any concerns utilizing apremilast for psoriatic arthritis in patients who are also taking roflumilast for COPD?

1 Answer available

What are your top takeaways from ACR 2022?

4 Answers available

How do you approach the continued use of TNF inhibitors in a patient with inflammatory arthritis who develops a positive dsDNA without clinical evidence of drug-induced lupus?

2 Answers available

What is your approach to tapering therapy in a patient with recurrent pericarditis now well-controlled on rilonacept?

2 Answers available

How do you approach Covid vaccine counseling in patients with rheumatic disease and history of pericarditis/serositis?

1 Answer available

Do you recommend continuous antibiotic prophylaxis for patients on complement inhibitors such as eculizumab?

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

3 Answers available

How do you approach the workup of a patient with incidentally found pachymeningitis?

1 Answer available

What is your approach to using apremilast for psoriatic arthritis in patients with history of depression?

1 Answer available

How do you assess potential fetal harm in patients who have unplanned pregnancy while taking teratogenic medications?

1 Answer available

When considering the use of DOACs in APLS, does the number of positive APLS antibodies influence your decision?

2 Answers available

What is your treatment algorithm for management of retroperitoneal fibrosis that does not respond to high-dose glucocorticoids?

1 Answer available

When would you consider rituximab as induction therapy in IgG4-related disease?

4 Answers available

Do you avoid intra-articular and bursa/tendon sheath corticosteroid injections in patients with a history of avascular necrosis?

2 Answers available

How do you manage nausea in the setting of hydroxychloroquine use?

1 Answer available

Do you utilize ethyl chloride spray prior to steroid injections?

1 Answer available

Would you intensify therapy in IgG4 related disease based solely on a persistently significantly elevated IgG4 level when all disease manifestations and inflammatory markers have normalized?

1 Answer available

In patients who develop a VTE, what conditions do you consider as persistent, provoking risk factors, and at what point are they controlled enough to stop anticoagulation?

I.e., what constitutes well-controlled cancer, IBD, nephrotic syndrome, etc. What other diseases do you put in this category (obesity, autoimmune dise...

1 Answer available

How would you manage polymyalgia rheumatica refractory to prednisone, methotrexate and tocilizumab?

Patient has no current evidence of underlying vasculitis or malignancy.

2 Answers available

How do you evaluate patients who have panuveitis without any systemic symptoms?

1 Answer available

Do you refer all patients with a Beighton score over 5 to genetics for further assessment?

2 Answers available

Would you favor stopping hydralazine in a patient requiring it for refractory hypertension if they also have a high titer ANA in the absence of any SLE symptoms?

2 Answers available

What is the role of synovectomy in the diagnosis and management of patients with inflammatory arthritis?

1 Answer available

What is your approach to the workup for an underlying systemic condition in a patient presenting with retinal vasculitis?

1 Answer available

How do you evaluate livedo reticularis (not livideo racemosa)?

Does your evaluation hinge on nonresolution with warming? How extensive is your workup?

1 Answer available

When do you consider vascular imaging in patients with Raynaud's and what type of imaging modalities do you utilize?

1 Answer available

How do you manage psoriatic arthritis in patients who are planning to start treatment with checkpoint inhibitors for underlying malignancy?

2 Answers available

What is your approach to workup for an underlying disorder in a patient with bilateral hip avascular necrosis?

1 Answer available

How do you approach CV risk assessment in RA patients when RA itself is associated with some degree of increased CV risk at baseline?

Recent articles regarding the use of JAK-Inhibition in RA have suggested to avoid in patients with increased CV risk. However, RA itself is cons...

2 Answers available

What is the role of non-prednisone oral glucocorticoids in the management of systemic rheumatologic disease?

Such as oral methylprednisolone, dexamethasone, prednisolone, etc.

1 Answer available

Which medications have the lowest risk of tuberculosis reactivation in patients with uncertain tuberculosis history and active rheumatologic disease?

2 Answers available

What is the difference between Multisystem Inflammatory Syndrome in Adults (MIS-A) and MAS/HLH?

1 Answer available

Does calcinosis appear differently in patients with dermatomyositis compared to systemic sclerosis?

1 Answer available

Do you treat fibromyalgia in your practice or do you refer back to PCP after ruling out autoimmune inflammatory pathology?

3 Answers available

How do you utilize methotrexate and/or hydroxychloroquine in the setting of limited scleroderma/CREST?

1 Answer available

Do you recommend routine use of Evusheld for pre-exposure prophylaxis for patients on immunosuppression?

Does treatment with B-cell depletion and/or negative anti-spike antibody status despite COVID mRNA vaccination influence your decision?

1 Answer available

Is there a role for regular hepatitis and TB screening in patients on chronic immunosuppressive therapy in the absence of new risk factors or exposures?

1 Answer available

Are there any known contraindications for IL-23 use in patients with psoriatic arthritis and CKD or ESRD?

1 Answer available

How do you think about biologic use in patients with underlying HIV infection?

2 Answers available

Do you hold tocilizumab for patients who are diagnosed with Covid and are with mild to moderate symptoms or non-hospitalized?

1 Answer available

What is your approach to evaluation of underlying autoimmune disease in patients with bilateral scleromalacia?

1 Answer available

How do you treat post-IVIG headache that is not responsive to Tylenol or NSAIDs?

Specifically, how do you treat the delayed headache, not the headache that develops during the infusion where pre-hydration and slowing down the rate ...

4 Answers available

Is there a role for prednisolone over prednisone in rheumatic patients with hepatic impairment?

1 Answer available

When a patient with a preexisting rheumatic disease and on immunotherapy begins to flare, how do you decide if this is an underlying rheumatic disease activity versus an immunotherapy related adverse event?

How do you decide if it may be safe to continue immunotherapy?

1 Answer available

Given the "LDL Paradox", in which RA patients with the highest levels of inflammation can have ultra-low levels of LDL (<70), how do you approach initiation of statin therapy in these patients?

Dr. Charles-Schoeman presented data at ACR 21 showing that, paradoxically, there is a U-shaped relationship between inflammation and LDL levels in pat...

1 Answer available

Is there a role for antibody testing to confirm vaccine response for patients on rituximab after COVID-19 vaccination?

1 Answer available

When would you consider checking JC virus prior to initiating biologic therapy?

1 Answer available

How will you use REGEN-COV (casirivimab/imdevimab-monoclonal antibody treatment recently approved under EUA as post-exposure prophylaxis for Covid) in rheumatic patients on immunosuppressive therapy?

Would you consider this for patients on B-cell depleting therapies or more broadly for other immunosuppressive agents?

2 Answers available

What is your management approach for patients with Adult Onset Still's who are planning pregnancy?

1 Answer available

What are your recommendations regarding methotrexate usage in patients with persistent chest CT changes post COVID pneumonia?

Would you have a different opinion based on whether it is a new therapy or an existing and previously well-tolerated therapy for the patient?

2 Answers available

How do you diagnose and treat patients who develop uveitis while on bisphosphonate therapy for osteoporosis?

Are there specific features that suggest drug-induced uveitis versus de novo uveitis?

1 Answer available

How are you timing the third dose of the COVID-19 mRNA vaccine in patients on rituximab?

1 Answer available

What is your differential for a patient presenting with multiple digits affected by flexor tenosynovitis, dupuytren's, and no evidence of peripheral inflammatory arthritis?

1 Answer available

How do you approach folate supplementation for methotrexate-related side effects?

3 Answers available

What is your approach to monitoring lipids in patients with rheumatic diseases such as RA and SLE and do you have a lower threshold to start lipid lowering agents compared to the general population?

2 Answers available

Are there any specific circumstances when you would consider the use of immunosuppression for DISH?

There is some emerging evidence that there is an inflammatory component.

1 Answer available

How would you counsel a patient who is interested in using supplements (such as fish oil or turmeric) as an adjunct to treatment of inflammatory arthritis?

3 Answers available

How do you approach the treatment of eosinophilic fasciitis refractory to glucocorticoids and methotrexate?

1 Answer available

Would you consider using a TNFi in a patient with a family history of demyelinating disease, in the absence of a personal history?

2 Answers available

How do you approach management of patients with inflammatory arthritis who are asymptomatic but develop radiographic progression?

1 Answer available

What is your threshold for number of alcoholic drinks per week before reconsidering prescribing methotrexate/leflunomide?

1 Answer available

How do you approach the use of biologics in patients with a history of Guillain-Barre syndrome?

1 Answer available

What is your approach to managing abnormal lipids in a patient on tocilizumab?

1 Answer available

How do you approach the treatment of inflammatory polyarthritis in patients with myelodysplastic syndromes?

2 Answers available

How do you approach the evaluation of patients referred for chronic lyme disease and counsel patients regarding this entity?

1 Answer available

Do you extrapolate from uveitis treatment pathways when managing other inflammatory eye conditions such as atypical serpiginous choroiditis?

2 Answers available

Do you switch to certolizumab in RA patients who are doing well on other TNFis and planning to become pregnant?

1 Answer available

How does a history of splenectomy alter how you counsel patients on the infection risk of TNF inhibitors or other biologics?

1 Answer available

Are you recommending the mRNA COVID-19 vaccines to your patients with immune mediated inflammatory diseases?

5 Answers available

Do you recommend shingles vaccine to all immunosuppressed patients under the age of 50 y.o.?

1 Answer available

Do you correct the synovial fluid white blood cell count for red blood cells, and if so, is there a rough approximation/equation you use?

2 Answers available

How do you approach patients with overlapping features of PMR and seronegative RA?

1 Answer available

How do you handle hypogammaglobulinemia detected in patients prior to maintenance rituximab infusion?

2 Answers available

Would you hold all immunosuppressive medications for the first month of LTBI treatment, or just biologics?

1 Answer available

How do you interpret a high positive RNP in the setting of a negative ANA and negative sm/RNP?

To my understanding, sm/RNP should also be positive in this situation (and one would assume a positive ANA as well)

1 Answer available

Is there an increased risk of COVID-19 in patients on immunosuppressants?

1 Answer available

Do you avoid any specific biologic therapies in HIV positive patients?

1 Answer available

What is your inflammatory arthritis differential when a patient presents with unilateral TMJ synovitis?

2 Answers available

What are examples of rheumatology quality measures that are both clinically meaningful and can be captured accurately and efficiently?

1 Answer available

Which steroid-sparing agent do you prefer to treat multi-organ Sweet's syndrome?

1 Answer available

Do you follow patients with elevated ESR/CRP if their work-up for rheumatologic etiology is unrevealing and no other cause is identified?

2 Answers available

What would be your differential for a wrist monoarthritis in an elderly female with erosions on MRI after less than 3 months of symptoms?

1 Answer available

How do you manage patients who are Hepatitis B core antibody positive/surface antigen negative and starting a biologic DMARD (other than rituximab)?

1 Answer available

Is there a role for tocilizumab in treatment of polymyalgia rheumatica in patients who do not have features of giant cell arteritis or rheumatoid arthritis?

1 Answer available

Are there any clinical situations in which checking for anti-chromatin antibodies is helpful?

1 Answer available

Papers discussed in this category

Arthritis Rheumatol, 2016 Jan

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

Arthritis and rheumatism, 1982-11

The 1982 revised criteria for the classification of systemic lupus erythematosus.

Arthritis and rheumatism, 2012-08

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.

, 2019 Aug 06

2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus.

Arthritis Rheum.,

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.

Brief Report: A Prospective Open-Label Phase IIa Trial of Tocilizumab in the Treatment of Polymyalgia Rheumatica.

Arthritis care & research, 2017-03

Rates of Serious Infections in HIV-Infected Patients Receiving Tumor Necrosis Factor Inhibitor Therapy for Concomitant Autoimmune Diseases.

Clin Exp Dermatol, 2018 May 24

Treatment of psoriasis with ustekinumab in a patient with HIV-related Kaposi sarcoma.

Eur J Rheumatol, 2017 Feb 23

Management of the temporomandibular joint in inflammatory arthritis: Involvement of surgical procedures.

Rev Bras Reumatol Engl Ed, 2016 Mar 16

What rheumatologists should know about orofacial manifestations of autoimmune rheumatic diseases.

Southern medical journal, 2016-11

Effects of Statin Therapy in Patients with Systemic Lupus Erythematosus.

Annals of the rheumatic diseases, 2011-05

Lupus Atherosclerosis Prevention Study (LAPS).

Atherosclerosis, 2015 Aug 28

Statin reduces mortality and morbidity in systemic lupus erythematosus patients with hyperlipidemia: A nationwide population-based cohort study.

N Engl J Med, 2020 Apr 29

Covid-19 in Immune-Mediated Inflammatory Diseases - Case Series from New York.

JAMA network open, 2018-11-02

Association of Immunoglobulin Levels, Infectious Risk, and Mortality With Rituximab and Hypogammaglobulinemia.

The Journal of arthroplasty, 2008-02

Determining "true" leukocytosis in bloody joint aspiration.

N Engl J Med,

Clinical practice. Care of the asplenic patient.

Mediterr J Rheumatol, 2020 Jun 11

Infections in Patients with Rheumatoid Arthritis in the Era of Targeted Synthetic Therapies.

Clin Infect Dis,

Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease.

Cochrane Database Syst Rev, 2013 May 31

Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.

British journal of cancer, 2023 Feb 04

Use of methotrexate and risk of skin cancer: a nationwide case-control study.

Ann Rheum Dis, 2017 Mar 23

Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate.

Clin Pharmacokinet,

Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids.

Gut,

Impaired conversion of prednisone to prednisolone in patients with liver cirrhosis.

Arthritis and rheumatism, 2001-12

Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides.

J Med Food,

Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Int J Clin Pract, 2021 Apr 29

Curcumin and rheumatoid arthritis: A systematic review of literature.

Nutrients, 2020 Dec 11

Efficacy of Spice Supplementation in Rheumatoid Arthritis: A Systematic Literature Review.

Current rheumatology reports, 2009-10

Diffuse idiopathic skeletal hyperostosis: differentiation from ankylosing spondylitis.

Radiology,

Radiographic and pathologic features of spinal involvement in diffuse idiopathic skeletal hyperostosis (DISH).

Curr Rheumatol Rep, 2021 Jan 26

Diffuse Idiopathic Skeletal Hyperostosis (DISH) and a Possible Inflammatory Component.

Kidney international, 2009-12

A prospective study of protein excretion using short-interval timed urine collections in patients with lupus nephritis.

Clinical journal of the American Society of Nephrology : CJASN, 2010-07

Comparison of urinary albumin-creatinine ratio and albumin excretion rate in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study.

Journal of the American Society of Nephrology : JASN, 2010-08

Comparison of different measures of urinary protein excretion for prediction of renal events.

Am J Kidney Dis, 2016 Sep 16

Timed Urine Collections for Albumin and Protein: "The King Is Dead, Long Live the King!".

J Rheumatol, 2004 Aug

Urine protein-to-creatinine ratio is a reliable measure of proteinuria in lupus nephritis.

N Engl J Med, 2021 Aug 04

Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19.

Curr Opin Rheumatol,

Retinal vasculitis.

BMJ Open, 2019 May 05

Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts.

Rheumatol Int, 2021 Jan 29

Does methotrexate cause progressive fibrotic interstitial lung disease? A systematic review.

Rheumatology (Oxford),

Five successful pregnancies with antenatal anakinra exposure.

Z Rheumatol,

[IL-1-blockade with Anakinra during pregnancy : Retrospective analysis of efficacy and safety in female patients with familial Mediterranean fever].

Journal of neurovirology, 2018-06

Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event.

Blood Adv,

American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism.

Annals of the rheumatic diseases, 2012-08

Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response.

Lupus,

Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis.

Arthritis Rheumatol, 2020 Jan 07

Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy.

J Rheumatol, 2013 Nov 15

Experiences with rituximab for the treatment of autoimmune diseases with ocular involvement.

Arthritis Res Ther, 2005 Mar 01

Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: a French national survey.

JAMA Ophthalmol, 2015 Oct

Association of systemic lupus erythematosus with uveitis.

JAMA, 2022 Oct 11

Hydroxychloroquine Dose per Ophthalmology Guidelines and the Risk of Systemic Lupus Erythematosus Flares.

Front Immunol, 2021 May 14

A Review of the Various Roles and Participation Levels of B-Cells in Non-Infectious Uveitis.

J Rheumatol, 2019 Apr 01

Therapy with Biologic Agents After Diagnosis of Solid Malignancies: Results from the Corrona Registry.

RMD Open,

How do we use biologics in rheumatoid arthritis patients with a history of malignancy? An assessment of treatment patterns using Scandinavian registers.

Curr Med Chem,

Targeting IL-17 and IL-23 in Immune Mediated Renal Disease.

Pathology, 2017 Mar 11

The role of interleukin-17A in the pathogenesis of kidney diseases.

Lancet,

Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial.

The Lancet. Respiratory medicine, 2016-09

Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial.

Annals of the rheumatic diseases, 2015-06

Rituximab for IgG4-related disease: a prospective, open-label trial.

Neth J Med,

The treatment outcomes in IgG4-related disease.

Medicine (Baltimore),

Therapeutic approach to IgG4-related disease: A systematic review.

Ann Rheum Dis, 2016 Oct 03

EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update.

ACR Open Rheumatol, 2021 Aug 25

Performance of Cytokine Storm Syndrome Scoring Systems in Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children.

Arthritis Res Ther, 2021 Mar 22

Vision loss in patients with giant cell arteritis treated with tocilizumab.

Scientific reports, 2017 Aug 10

Analysis of Factors Influencing Diagnostic Accuracy of T-SPOT.TB for Active Tuberculosis in Clinical Practice.

J Orthop Translat, 2020 Jan 06

Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version).

Annals of internal medicine, 2018-01-16

Use of Immune Checkpoint Inhibitors in the Treatment of Patients With Cancer and Preexisting Autoimmune Disease: A Systematic Review.

J Immunother Cancer,

Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders.

Autoimmun Rev, 2012 Nov 30

Immunogenicity and autoimmunity during anti-TNF therapy.

Arthritis Rheum,

Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis.

Arthritis care & research, 2014-08

Identification of risk factors for elevated transaminases in methotrexate users through an electronic health record.

Intern Med J, 2022 Mar 16

Assessment of liver fibrosis markers in people with rheumatoid arthritis on methotrexate.

Ann Rheum Dis, 2016 Feb 17

The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation.

Support Care Cancer, 2019 Dec 13

Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study.

Int J Surg Case Rep, 2020 Nov 22

Destructive Osteonecrosis of the Femoral Head After a Single Intra-Articular Corticosteroid Injection: A Report of Two Cases.

Eur J Orthop Surg Traumatol, 2019 Sep 19

Avascular necrosis of the femoral head after single steroid intra-articular injection.

Annals of the rheumatic diseases, 2019-10

EULAR recommendations for the management of antiphospholipid syndrome in adults.

J Thromb Haemost, 2020 Nov 29

Trial of Rivaroxaban in AntiPhospholipid Syndrome (TRAPS): Two-year outcomes after the study closure.

Front Cardiovasc Med, 2021 Aug 03

Use of Direct Oral Anticoagulants in Patients With Antiphospholipid Syndrome: A Systematic Review and Comparison of the International Guidelines.

Medizinische Klinik (Munich, Germany : 1983), 2002-11-15

[Prevalence of circulating autoantibodies in healthy individuals].

Journal for scientific research. Medical sciences, 2001 Apr

Occurence of autoantibodies in healthy Omani individuals.

Clin Microbiol Infect, 2018 Feb 07

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Introduction).

Arthritis & rheumatology (Hoboken, N.J.), 2018-03

The Science Behind Biosimilars: Entering a New Era of Biologic Therapy.

N Engl J Med, 2020 Nov 16

Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis.

Clinical pharmacokinetics, 2018-12

Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease.

Frontiers in immunology, 2018

Reversing Autoimmunity Combination of Rituximab and Intravenous Immunoglobulin.

Clinical immunology (Orlando, Fla.), 2020 Jul 15

The potential impact of timing of IVIG administration on the efficacy of rituximab for immune tolerance induction for patients with Pompe disease.

The Pediatric infectious disease journal, 2018 Oct

Infliximab Plus Intravenous Immunoglobulin (IVIG) Versus IVIG Alone as Initial Therapy in Children With Kawasaki Disease Presenting With Coronary Artery Lesions: Is Dual Therapy More Effective?

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017 Nov 03

Successful IVIG treatment without discontinuation of TNF-α blocker in Guillain-Barre syndrome induced by adalimumab in patient with Crohn's disease.

N Engl J Med,

Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis.

Ann Rheum Dis, 2022 Sep 22

Risk of major adverse cardiovascular events with tofacitinib versus tumour necrosis factor inhibitors in patients with rheumatoid arthritis with or without a history of atherosclerotic cardiovascular disease: a post hoc analysis from ORAL Surveillance.

Rheumatology (Oxford), 2014 Sep 16

Differentiation between osteoarthritis and psoriatic arthritis: implications for pathogenesis and treatment in the biologic therapy era.

Current medical research and opinion, 2016-12

Corticosteroids: the knee jerk response.

Open access rheumatology : research and reviews, 2016

Polymyalgia rheumatica: observations of disease evolution without corticosteroid treatment.

PET Clin, 2020 Feb 11

18F-Fluorodeoxyglucose PET/Computed Tomography in the Diagnosis and Monitoring of Giant Cell Arteritis.

Rheumatology (Oxford), 2022 Jul 22

PET/CT of cranial arteries for a sensitive diagnosis of giant cell arteritis.

Arthritis and rheumatism, 2008-09

Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2014-12

Curr Rheumatol Rep, 2022 Feb 15

Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response.

Arthritis Care Res (Hoboken), 2017 Dec

Impact of Obesity and Adiposity on Inflammatory Markers in Patients With Rheumatoid Arthritis.

JAMA, 1999 Dec 08

Elevated C-reactive protein levels in overweight and obese adults.

Reumatologia, 2020 Feb 28

The impact of obesity on inflammatory markers used in the assessment of disease activity in rheumatoid arthritis - a cross-sectional study.

Pediatr Blood Cancer, 2021 Oct

Idiopathic multicentric Castleman disease with TAFRO clinical subtype responsive to IL-6/JAK inhibition: A pediatric case series.

Int. J. Radiat. Oncol. Biol. Phys.,

Radiotherapy optimization in early-stage Dupuytren's contracture: first results of a randomized clinical study.

The New England journal of medicine, 2003-10-16

Development of autoantibodies before the clinical onset of systemic lupus erythematosus.

Rheumatology (Oxford, England), 2018-09-01

The SLE-key test serological signature: new insights into the course of lupus.

Lupus, 2021 Jan 05

Delayed diagnosis adversely affects outcome in systemic lupus erythematosus: Cross sectional analysis of the LuLa cohort.

Arthritis Rheumatol, 2018 Jun 27

Brief Report: Lupus-An Unrecognized Leading Cause of Death in Young Females: A Population-Based Study Using Nationwide Death Certificates, 2000-2015.

J Manag Care Spec Pharm, 2022 Jul 01

Complement activation products vs standard ANA testing: Treatment outcomes, diagnosis, and economic impact (CAPSTONE) in systemic lupus erythematosus.

Diagnostics (Basel), 2021 Sep 01

Anti-DFS70 Antibodies for Differentiating Systemic Autoimmune Rheumatic Disease in Patients with Positive ANA Tests: A Systematic Review and Meta-Analysis.

Front Immunol, 2021 May 27

Autoantibody Discovery, Assay Development and Adoption: Death Valley, the Sea of Survival and Beyond.

Chest, 2021 Feb

Consensus Guidelines for Evaluation and Management of Pulmonary Disease in Sjögren's.

Expert review of clinical immunology, 2015 Dec 22

Early diagnosis of primary Sjögren's syndrome: EULAR-SS task force clinical recommendations.

The neurologist, 2017 Jul

Spectrum of Autonomic Nervous System Impairment in Sjögren Syndrome.

Arthritis Rheumatol, 2020 Apr

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Immunol Invest, 1985 Jun

Specificity of the Crithidia luciliae method for detecting anti-DNA antibodies. Effect of absorption for lipoproteins.

Int J Environ Res Public Health, 2021 Aug 01

Relationship of Hydroxychloroquine and Ophthalmic Complications in Patients with Type 2 Diabetes in Taiwan.

Arthritis Care Res (Hoboken), 2023 Feb 10

Occam's Razor Dulled: A Curious Case of Dyspnea in a 70-Year-Old.

J Am Dent Assoc, 2016 Jan 05

Clinical practice guidelines for oral management of Sjögren disease: Dental caries prevention.

Eur J Radiol, 2020 Jan 17

Ultrasound characterization of pseudoerosions and dorsal joint recess morphology of the hand and wrist in 100 asymptomatic subjects.

Joint Bone Spine, 2019 Jan 31

Ultrasonographic criteria for the diagnosis of erosive rheumatoid arthritis using osteoarthritic patients as controls compared to validated radiographic criteria.

Arthritis Rheumatol, 2020 Sep 6

Incidence, Clinical Features, and Outcomes of Late-Onset Neutropenia From Rituximab for Autoimmune Disease.

Arthritis and rheumatism, 2011-03

Evaluation of the safety of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis: results from a randomized controlled trial.

The Journal of rheumatology, 2013-05

Safety of rituximab in combination with other biologic disease-modifying antirheumatic drugs in rheumatoid arthritis: an open-label study.

Arthritis & rheumatology (Hoboken, N.J.), 2017-10

The Safety and Immunogenicity of Live Zoster Vaccination in Patients With Rheumatoid Arthritis Before Starting Tofacitinib: A Randomized Phase II Trial.

Arthritis Rheum, 2004 Oct

Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an open-label study.

N. Engl. J. Med., 2019 May 20

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease.

N Engl J Med, 2019 Sep 29

Nintedanib in Progressive Fibrosing Interstitial Lung Diseases.

Ther Adv Musculoskelet Dis, 2020 Nov 24

Efficacy of high-dose anakinra in refractory macrophage activation syndrome in adult-onset Still's disease: when dosage matters in overcoming secondary therapy resistance.

Blood advances, 2024 Aug 13

Long-term outcomes of peripheral blood stem cell unrelated donors mobilized with filgrastim.

Annals of oncology : official journal of the European Society for Medical Oncology, 2018 Sep 01

Overall survival and risk of second malignancies with cancer chemotherapy and G-CSF support.

J Rheumatol, 2006 Jul 01

Therapy with granulocyte colony-stimulating factor in systemic lupus erythematosus may be associated with severe flares.

Journal of pharmacy practice, 2021 Nov 08

Use of Colony-Stimulating Factors in Patients With Systemic Lupus Erythematosus.

Cleveland Clinic journal of medicine, 2016-01

Approach to asymptomatic creatine kinase elevation.

The British journal of dermatology, 2019-11

Utilization patterns and performance of commercial myositis autoantibody panels in routine clinical practice.

J Am Acad Dermatol, 2020 Sep 04

Accuracy of commercial panels to evaluate myositis autoantibodies: A single-institution perspective.

Rheumatology (Oxford),

The reliability of immunoassays to detect autoantibodies in patients with myositis is dependent on autoantibody specificity.

Medicine (Baltimore), 2016 Aug

Creatine kinase in the U.S. population: Impact of demographics, comorbidities, and body composition on the normal range.

BMJ, 2021 Jun 23

Investigating raised creatine kinase.

Arthritis and rheumatism, 2010-05

Assessment of cognitive function in systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis by computerized neuropsychological tests.

Ann Clin Transl Neurol, 2020 Jul 06

Cognitive impairment in patients with Neuro-Sjögren.

Lupus, 2023 Apr 10

In-person versus virtual administration of the American College of Rheumatology gold standard cognitive battery in systemic lupus erythematosus: Are they interchangeable?

Lupus Sci Med, 2022 Jan

To treat or not to treat with immunosuppressive therapy: psychiatric disorders in patients with systemic lupus erythematosus.

Nat Rev Nephrol, 2015 Nov 16

Renal involvement in primary Sjögren syndrome.

Arthritis & rheumatology (Hoboken, N.J.), 2018-06

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

Nat Med, 2022 Jun

Inching closer to precision treatment for rheumatoid arthritis.

Nat Med, 2022 May 19

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial.

Curr Opin Rheumatol, 2013 May

New learnings on the pathophysiology of RA from synovial biopsies.

Arthritis Res Ther, 2014 Apr 30

Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics.

Annals of clinical and laboratory science, 2008

Nephrotic range proteinuria: rare manifestation of scleroderma renal crisis.

International journal of general medicine, 2019 Sep 02

Renal pathology and clinical associations in systemic sclerosis: a historical cohort study.

Clinical rheumatology, 1988 Sep

Treatment of psoriatic arthritis with sulphasalazine: a one year open study.

Journal of the American Academy of Dermatology, 1987 Apr

Gold therapy and its indications in dermatology. A review.

Journal of the American Academy of Dermatology, 2020 May 19

Hydroxychloroquine effects on psoriasis: A systematic review and a cautionary note for COVID-19 treatment.

Ophthalmology and therapy, 2023 Aug 21

Cataract Surgery Outcomes in Patients with Non-ocular Autoimmune Disease.

Ann Rheum Dis, 2020 Jan

The 2019 American College of Rheumatology/European League Against Rheumatism classification criteria for IgG4-related disease.

Mediterranean journal of rheumatology, 2022 Mar 31

Clinical Phenotype and Mechanisms of Leukopenia/Neutropenia in Patients with Primary Sjögren's Syndrome.

Annals of the rheumatic diseases, 2018-09

Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study.

Arthritis & rheumatology (Hoboken, N.J.), 2019-02

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis.

RMD open, 2020 Feb

Effects of ustekinumab on spondylitis-associated endpoints in TNFi-naïve active psoriatic arthritis patients with physician-reported spondylitis: pooled results from two phase 3, randomised, controlled trials.

The New England journal of medicine, 2014 Jun 05

Once-weekly dalbavancin versus daily conventional therapy for skin infection.

Trials, 2022 Sep 05

Efficacy and safety of guselkumab in biologic-naïve patients with active axial psoriatic arthritis: study protocol for STAR, a phase 4, randomized, double-blinded, placebo-controlled trial.

Arthritis Care Res (Hoboken), 2016 Jan

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

Alimentary pharmacology & therapeutics, 2022 May 20

Review article: latent tuberculosis in patients with inflammatory bowel diseases receiving immunosuppression-risks, screening, diagnosis and management.

Arthritis & rheumatology (Hoboken, N.J.), 2015-05

Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.

International journal of rheumatic diseases, 2014-02

Neurosarcoidosis mimicking multiple sclerosis successfully treated with methotrexate and adalimumab.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18

Efficacy Results of a 52-week Trial of Adalimumab in the Treatment of Refractory Sarcoidosis.

Clinical nuclear medicine, 2016-05

FDG PET/CT Evidence of Effective Treatment of Cardiac Sarcoidosis With Adalimumab.

J Investig Med High Impact Case Rep, 2021 Jan-Dec

Pituitary Sarcoidosis in a Pediatric Patient Successfully Treated With Adalimumab and Methotrexate.

Clinical therapeutics, 2018 Feb

Methotrexate Dose in Patients With Early Rheumatoid Arthritis Impacts Methotrexate Polyglutamate Pharmacokinetics, Adalimumab Pharmacokinetics, and Efficacy: Pharmacokinetic and Exposure-response Analysis of the CONCERTO Trial.

Clinical and experimental dermatology, 2021 Mar 09

Brodalumab-induced subacute cutaneous lupus erythematosus.

JAAD case reports, 2019 Mar 01

Ustekinumab-induced subacute cutaneous lupus.

Dermatologic therapy, 2020 May 03

Secukinumab-induced subacute cutaneous lupus erythematosus.

The Journal of allergy and clinical immunology, 2012 Feb 14

Chronic urticaria and autoimmunity: associations found in a large population study.

BMC nephrology, 2019 Oct 31

Clinical practice guideline on pregnancy and renal disease.

Medicine, 2014 Oct

Intravenous immunoglobulin in the therapeutic armamentarium of systemic lupus erythematosus: a systematic review and meta-analysis.

Blood, 2022 Jun 23

Advancing therapeutic complement inhibition in hematologic diseases: PNH and beyond.

Best practice & research. Clinical rheumatology, 2019 Dec 19

Antiphospholipid syndrome.

Blood, 2011-02-03

Pregnancy outcomes after maternal exposure to rituximab.

Arthritis Care Res (Hoboken), 2020 Apr

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Journal of clinical medicine, 2023 Feb 24

Kidney Biopsy in Pregnant Women with Glomerular Diseases: Focus on Lupus Nephritis.

Autoimmunity reviews, 2018 Apr 07

Antinuclear antibodies: Is the indirect immunofluorescence still the gold standard or should be replaced by solid phase assays?

The ocular surface, 2015 Jan 15

Clinical guidelines for management of dry eye associated with Sjögren disease.

Arthritis and rheumatism, 2011-12

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus.

N Engl J Med,

Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.

Arthritis Rheumatol, 2017 Apr 07

Efficacy and Safety of Subcutaneous Belimumab in Systemic Lupus Erythematosus: A Fifty-Two-Week Randomized, Double-Blind, Placebo-Controlled Study.

Lancet (London, England), 2011 Feb 04

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial.

Annals of internal medicine, 2004-10-05

Prednisone plus methotrexate for polymyalgia rheumatica: a randomized, double-blind, placebo-controlled trial.

The New England journal of medicine, 2023 Oct 05

Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper.

Annals of the rheumatic diseases, 1996 Apr

Can methotrexate be used as a steroid sparing agent in the treatment of polymyalgia rheumatica and giant cell arteritis?

The Journal of rheumatology, 1996 Sep

The use of methotrexate in polymyalgia rheumatica.

International journal of clinical pharmacology and therapeutics, 2021 May

Methotrexate for treating polymyalgia rheumatica: A meta-analysis of randomized controlled trials.

Annals of the rheumatic diseases, 2022 Feb 24

Tocilizumab in patients with new onset polymyalgia rheumatica (PMR-SPARE): a phase 2/3 randomised controlled trial.

JAMA, 2022 Sep 20

Effect of Tocilizumab on Disease Activity in Patients With Active Polymyalgia Rheumatica Receiving Glucocorticoid Therapy: A Randomized Clinical Trial.

Ann Rheum Dis, 2015 Oct

2015 Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.

Arthritis care & research, 2023 Aug 10

Treatment of Polymyalgia Rheumatica by Rheumatology Providers: Analysis from the American College of Rheumatology RISE Registry.

Arthritis care & research, 2023 Oct 26

2022 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis.

Rheumatology advances in practice, 2021 Nov 27

Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study.

Rheumatology (Sunnyvale, Calif.), 2015 May 07

Polymyalgia Rheumatica and its Association with Cancer.

Annals of the rheumatic diseases, 2013 Jul 10

Is cancer associated with polymyalgia rheumatica? A cohort study in the General Practice Research Database.

Journal of behavioral medicine, 2023 Jun 29

Self-guided digital acceptance and commitment therapy for fibromyalgia management: results of a randomized, active-controlled, phase II pilot clinical trial.

Seminars in arthritis and rheumatism, 2018 Jan 06

Abatacept in patients with rheumatoid arthritis and interstitial lung disease: A national multicenter study of 63 patients.

Annals of the rheumatic diseases, 2023 Aug 28

2023 ACR/EULAR antiphospholipid syndrome classification criteria.

Rheumatology and therapy, 2021 Jan 09

Antiphospholipid Antibodies in Inflammatory and Autoimmune Rheumatic and Musculoskeletal Diseases Beyond Lupus: A Systematic Review of the Available Evidence.

Arthritis & rheumatology (Hoboken, N.J.), 2023 Aug 28

The 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria.

International journal of clinical pharmacology and therapeutics, 2014 Jan

Assessment of disease-drug-drug interaction between single-dose tocilizumab and oral contraceptives in women with active rheumatoid arthritis.

Science (New York, N.Y.), 1982-04-23

Systemic lupus erythematosus-like syndrome in monkeys fed alfalfa sprouts: role of a nonprotein amino acid.

Arthritis care & research, 2017-03

Influence of Alcohol Consumption on the Risk of Systemic Lupus Erythematosus Among Women in the Nurses' Health Study Cohorts.

Arthritis & rheumatology (Hoboken, N.J.), 2017-11

Association of Trauma and Posttraumatic Stress Disorder With Incident Systemic Lupus Erythematosus in a Longitudinal Cohort of Women.

Lupus, 2018-08

Less than 7 hours of sleep per night is associated with transitioning to systemic lupus erythematosus.

Cell host & microbe, 2019-01-09

A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity.

Lupus, 2018 Oct 11

Pesticide exposure and risk of systemic lupus erythematosus in an urban population of predominantly African-American women.

Arthritis care & research, 2022 Oct 11

Association of Healthy Lifestyle Behaviors and the Risk of Developing Rheumatoid Arthritis Among Women.

BMJ (Clinical research ed.), 2022 Jan 26

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial.

Clinical and experimental immunology, 2003 Mar

Silica accelerated systemic autoimmune disease in lupus-prone New Zealand mixed mice.

Environmental health perspectives, 2005 Dec

Phthalate linked to lupus in mice.

Lupus, 2001

Diet and systemic lupus erythematosus: from mouse and monkey to woman?

Auto- immunity highlights, 2012 Jan 13

Hair dyes as a risk for autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015-08-01

Histoplasmosis complicating tumor necrosis factor-α blocker therapy: a retrospective analysis of 98 cases.

BMC public health, 2008 Jan 21

The SMILE study: a study of medical information and lifestyles in Eindhoven, the rationale and contents of a large prospective dynamic cohort study.

Current opinion in pulmonary medicine, 2013 Sep

Common variable immunodeficiency-associated granulomatous and interstitial lung disease.

Therapeutic drug monitoring, 2022 Jun 01

Drug-Drug Interactions Between Mycophenolic Acid and Proton Pump Inhibitors: A Systematic Review and Meta-Analysis.

The Journal of allergy and clinical immunology, 2021 Apr 20

Rituximab-induced hypogammaglobulinemia and infection risk in pediatric patients.

European journal of immunology, 2022 Aug 10

Secondary rituximab-associated versus primary immunodeficiencies: The enigmatic border.

Journal of autoimmunity, 2012 Feb 06

Peripheral neuropathies in Sjögren's syndrome: a critical update on clinical features and pathogenetic mechanisms.

Rheumatology (Oxford, England), 2013 Oct 25

Systemic involvement in primary Sjogren's syndrome evaluated by the EULAR-SS disease activity index: analysis of 921 Spanish patients (GEAS-SS Registry).

Annals of the rheumatic diseases, 2001 May

Acute arthritis after intra-articular hyaluronate injection: onset of effusions without crystal.

The Journal of rheumatology, 1997 May

Lack of pharmacokinetic interaction of meloxicam with methotrexate in patients with rheumatoid arthritis.

British journal of rheumatology, 1995 May

Total and free methotrexate pharmacokinetics, with and without piroxicam, in rheumatoid arthritis patients.

The Lancet. Neurology, 2009-08

Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment.

The Journal of infection, 2011-11

Norovirus gastroenteritis successfully treated with nitazoxanide.

Alimentary pharmacology & therapeutics, 2006 Nov 15

Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.

Journal of tropical medicine, 2017 Feb 26

Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country.

International journal of cardiology. Heart & vasculature, 2021 Apr 29

Non-steroidal treatment of cardiac sarcoidosis: A systematic review.

Annals of the rheumatic diseases, 2016-04

Impact of baseline anti-cyclic citrullinated peptide-2 antibody concentration on efficacy outcomes following treatment with subcutaneous abatacept or adalimumab: 2-year results from the AMPLE trial.

Arthritis research & therapy, 2021 Sep 18

HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA.

Lupus, 2014 Jul 30

Serious infections in systemic lupus erythematosus with a focus on pneumococcal infections.

MMWR. Morbidity and mortality weekly report, 2024 Sep 12

Use of 21-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024.

Arthritis Rheumatol, 2016 Oct 26

2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts.

Arthritis care & research, 2017 Oct 09

Subjective and Objective Measures of Dryness Symptoms in Primary Sjögren's Syndrome: Capturing the Discrepancy.

The Journal of rheumatology, 2021 May 01

Correlation Between Subjective and Objective Severity of Oral and Ocular Dryness in Primary Sjögren Syndrome.

Diabetes research and clinical practice, 1994 Jan

Insulin autoimmune syndrome (Hirata disease): clinical features and epidemiology in Japan.

Clinical endocrinology, 2020 Feb 26

Management of Insulin Autoimmune Hypoglycaemia: Single-centre experience from Western India with systematic review of world literature.

Journal of the Endocrine Society, 2022 Dec 02

Perioperative Evaluation and Management of Patients on Glucocorticoids.

Diagnostics (Basel, Switzerland), 2021 Apr 20

Glucocorticoid Withdrawal-An Overview on When and How to Diagnose Adrenal Insufficiency in Clinical Practice.

The American journal of medicine, 2024 Mar 16

The Contribution of 18F FDG PET-CT for the Investigation of Fever of Unknown Origin and Inflammation of Unknown Origin.

Autoimmunity reviews, 2009-02

The risk of ultraviolet radiation exposure from indoor lamps in lupus erythematosus.

Arthritis and rheumatism, 2013-07

Vitamin D in systemic lupus erythematosus: modest association with disease activity and the urine protein-to-creatinine ratio.

Arthritis care & research, 2016 Jan

Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.

Lupus, 2014 Feb 06

Vitamin D and cutaneous lupus erythematosus: effect of vitamin D replacement on disease severity.

Annals of the rheumatic diseases, 2023 Oct 12

EULAR recommendations for the management of systemic lupus erythematosus: 2023 update.

Arthritis care & research, 2023 Nov 28

Reference Range of Hydroxychloroquine Blood Levels That Can Reduce Odds of Active Lupus and Prevent Flares.

Journal of the American Academy of Dermatology, 2015 Jan 30

Influence of smoking on the efficacy of antimalarials in cutaneous lupus: a meta-analysis of the literature.

Journal of the European Academy of Dermatology and Venereology : JEADV, 2016 Dec 20

S2k guideline for treatment of cutaneous lupus erythematosus - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV).

Arthritis and rheumatism, 1988-07

The effects of leucovorin (folinic acid) on methotrexate therapy in rheumatoid arthritis patients.

Arthritis and rheumatism, 1993-06

Low-dose methotrexate with leucovorin (folinic acid) in the management of rheumatoid arthritis. Results of a multicenter randomized, double-blind, placebo-controlled trial.

The Journal of rheumatology, 2014 Apr 15

Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.

Autoimmunity reviews, 2023 Dec 20

Implementation of regulatory guidance for JAK inhibitors use in patients with immune-mediated inflammatory diseases: An international appropriateness study.

Rheumatology (Oxford, England), 2023 Dec 01

Anti-SAE autoantibody in dermatomyositis: original comparative study and review of the literature.

Clinical and experimental immunology, 2015 Apr

Usefulness of monitoring of B cell depletion in rituximab-treated rheumatoid arthritis patients in order to predict clinical relapse: a prospective observational study.

Ann Rheum Dis, 2014 Feb 13

The number of flares patients experience impacts on damage accrual in systemic lupus erythematosus: data from a multiethnic Latin American cohort.

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