Please select the option that best describes you:
Topics:
Internal Medicine • Rheumatology • Rheumatoid Arthritis • Sarcoidosis • Methotrexate • General Rheumatology • Gastroenterology • Pulmonology • General Hepatology • Hepatology & Liver Transplantation
Is there a role for the use of transient elastography (FibroScan) to monitor liver fibrosis in patients on long term methotrexate?
Answer from: at Academic Institution
Liver elastography is a useful tool to use when assessing the potential hepatotoxicity of various drug therapies. Traditionally, methotrexate accounted for nearly all the hepatotoxicity issues that we faced; however, we can add many other drugs to that list. Virtually, every immune suppressive drug ...
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Answer from: at Community Practice
No
Answer from: at Academic Institution
Factors that tend to increase the potential hepatotoxicity of MTX include obesity, as mentioned, diabetes, hyperlipidemia, alcohol, underlying liver disease such as latent hep C infection for example (I hep C screen everybody with RA and autoimmune disorders), fatty liver, and the concomitant use of...