Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?  

Interesting question. Not being an endocrinologist, I don't have the expertise to advise but the reference below makes the statement that even short-term steroids can be an issue. I suspect that if you have to stop abruptly from 60 mg daily for 2 weeks, it would probably be fine in most instances bu...

The simple answer to this is "no" but I think for a bigger picture of when to taper and how to taper, here is a recent link by Brett et al., NEJM Journal Watch 2024.

The answer is no, with some caveats. I recommend reviewing the paper by Cardenas et al., PMID 36545644.

Of course, I agree with my colleagues. But... for excellent reviews I must add the most recent open-access European Society of Endocrinology and Endocrine Society Joint Clinical Guidelines for Diagnosis and therapy of glucocorticoid-induced adrenal insufficiency by Beuschlein et al., PMID 3871...