Would you use TNF inhibitors in patients with features of SLE, but active peripheral and axial spondylarthritis?

Patient with sacroiliitis on imaging, failure of two NSAIDs.

Answer from: at Community Practice

I can understand Dr. @Andras Perl's hesitancy as there is no good literature to prove one way or the other. This is one of those questions which will have practitioners on both sides of the answer.However, I would not hesitate for several reasons:In the early 2000s, before we had better txs availabl...

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at NIAMS
We used to have the same debates with hydralazine ...

Answer from: at Academic Institution

I prefer to avoid TNF blockade in ANA+ patients with any clinical features of potentially overlapping SLE.

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Would you use TNF inhibitors in patients with features of SLE, but active peripheral and axial spondylarthritis?

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