Can lupus anticoagulant be positive despite a normal aPTT?

How often does this occur and does this lower your suspicion for a "true" or clinically significant lupus anticoagulant?

Answer from: Medical Oncologist at Academic Institution

aPTT is one of the assays that may be abnormal in the presence of lupus anticoagulant, but not always. Usually, when screening for lupus anticoagulant, there will be a "special" aPTT assay used that is a bit more sensitive to detect lupus anticoagulant. There are several different aPTT-based assays ...

Comments

at Uniformed Services University of the Health Sciences (USUHS)
Very interesting and informative, thanks!

at Mainehealth
Important information to consider.

at UTMB Health
Yes, as Dr. @Wysokinska explained there are two ty...

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Can lupus anticoagulant be positive despite a normal aPTT?

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