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Topics:
Pediatric Hematology/Oncology • Internal Medicine • Hematology • Pediatric Hematology • Benign Hematology • Hemostasis/Thrombosis
Can lupus anticoagulant be positive despite a normal aPTT?
How often does this occur and does this lower your suspicion for a "true" or clinically significant lupus anticoagulant?
Answer from: Medical Oncologist at Academic Institution
aPTT is one of the assays that may be abnormal in the presence of lupus anticoagulant, but not always. Usually, when screening for lupus anticoagulant, there will be a "special" aPTT assay used that is a bit more sensitive to detect lupus anticoagulant. There are several different aPTT-based assays ...
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