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Topics:
Pediatric Hematology/Oncology • Internal Medicine • Hematology • Pediatric Hematology • Benign Hematology • Von Willebrand • Hemostasis/Thrombosis
Is there any benefit to using desmopressin over vWF replacement therapy for vWD?
If not, has your practice changed to use vWF replacement therapy more routinely for perioperative or acute bleeding management? Do you still perform DDAVP response testing?
Answer from: at Academic Institution
For mild type 1 and 2A, we do offer DDAVP testing and use. It was a much more useful drug when it was widely available as a nasal spray. It still has its place, but with patients whose level of VWF is <20% baseline, we have a lot of treatment failures and end up using factor.
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