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Topics:
Pediatric Hematology/Oncology • Internal Medicine • Hematology • Sickle Cell • Pediatric Hematology • Benign Hematology
How would you approach secondary stroke prevention in an adult with Hemoglobin SC disease?
Would you consider chronic RBC exchange versus HU?
Answer from: at Academic Institution
Stroke is less common in HbSC disease than it is in HbS homozygotes (Ohene-Frempong et al., PMID 9414296). Thus, there are no studies focused on primary or secondary stroke prevention in HbSC disease. Recent guidelines for stroke management were “silent” on stroke in HbSC disease (DeBaun...
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