New: NCI-funded clinical trial search
Mednet Logo

Related Questions

How will you adjust your approach to steroid taper in patients with PMR also on sarilumab?

1
2 Answers

Mednet Member
Mednet Member
Rheumatology · Harvard Medical School- MGH

I would try to replicate the prednisone taper followed in the SAPHYR study that weaned patients off over 14 weeks, understanding that there may be patients that won’t be able to taper the prednisone so aggressively or may benefit, in the opinion of the treating physician, from longer tapers (e.g., 4...

How will you approach drug sequencing in patients with PMR given the SAPHYR data?

2
2 Answers

Mednet Member
Mednet Member
Rheumatology · Harvard Medical School- MGH

The SAPHYR study enrolled patients with PMR who relapsed while tapering prednisone at daily doses equal to or greater than 7.5 mg. One group of patients received sarilumab 200 mg every 2 weeks along with a 14-week prednisone taper and another group of patients received a placebo along with a 52-week...