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Topics:
Internal Medicine • Rheumatology • Hematology • Antiphospholipid Syndrome • Benign Hematology • General Rheumatology
When considering the use of DOACs in APLS, does the number of positive APLS antibodies influence your decision?
Answer from: at Academic Institution
The number of antibodies is an important consideration.On the one end of the spectrum, I would not recommend any DOACs in a triple positive APLS (especially with arterial thrombosis). Having said that, I would not change treatment in a triple positive APLS patient if they were started on DOACs in th...
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Answer from: at Academic Institution
I agree with Dr. @Broder's comments. The number of positive antibodies, their titers, and whether they are persistently positive versus intermittently positive all matter. Although warfarin is preferred in classic APS, I have seen patients with APS started on DOAC by hematologists, and they have don...