What is the recommended fungal workup in an immunocompromised patient after 5 days of persistent fever?

For any patient with fevers, I focus significantly on any symptoms that a patient might have, like headache, diarrhea, and sinus symptoms, and work up a differential diagnosis based on possible pathogens in this area. If I am not finding anything, I would obtain a CT chest/abd/pelvis, as both invasi...

CT chest at the very least, regardless of symptoms.

Serum galactomannan.

I tend to find BDG worthless/problematic.

It is important to obtain a CT chest despite a normal chest x-ray, including in patients with fever and with or without respiratory symptoms. It is not uncommon to see abnormal CT chest findings, with no resp symptoms/signs. Fever may be the only abnormality. In many cases, radiology is more reliabl...

Blastomycosis doesn't have good serological testing in my limited experience of seeing it. Wonder what you all would do to approach that question. I have had a few cases of patients present as if they had rheumatologic ILD or ANCA vasculitis, only later to realize that it was blastomycosis diagnosed...