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Topics:
Internal Medicine • Rheumatology • Systemic sclerosis • General Rheumatology • Scleroderma • Pulmonology • Nephrology • Scleroderma Renal Crisis • Critical Care
What are some important considerations for use of ACE inhibition in scleroderma renal crisis patients who require dialysis?
For example, is captopril dialyzable?
Answer from: at Academic Institution
Yes, captopril is dialyzable with about ~35% of the drug being removed during intermittent hemodialysis. It is not recommended to be used if an AN69 hemofilter is used for iHD, as it is associated with anaphylaxis with that particular filter.
There does not appear to be any contraindications to u...
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