How long would you wait to start another biologic agent after Rituximab administration in patients with dermatomyositis and refractory inflammatory arthritis (intolerant to traditional DMARDs)?

Patient with dermatomyositis on rituximab with refractory inflammatory arthritis. Intolerant of traditional DMARDs such as methotrexate, leflunomide, hydroxychloroquine, and azathioprine

Answer from: at Academic Institution

The time frame between rituximab infusion and initiation of a different biologic agent depends on the severity of the symptoms. In case of life-threatening complications (like RP-ILD), then rituximab could be given simultaneously with an agent like tofacitinib. If the main symptom though is arthriti...

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How long would you wait to start another biologic agent after Rituximab administration in patients with dermatomyositis and refractory inflammatory arthritis (intolerant to traditional DMARDs)?

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