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Topics:
Internal Medicine • Rheumatology • Sarcoidosis • General Rheumatology • Pulmonology • ILD • CTD-ILD
Is it safe to combine mycophenolate and adalimumab for management of pulmonary sarcoidosis in a patient that could not tolerate methotrexate?
Answer from: at Academic Institution
Combination therapy is often required in patients with sarcoidosis. Combination of adalimumab with other immunosuppressants, such as methotrexate, leflunomide, azathioprine, or mycophenolate, can be used, with close monitoring of labs (CBC, CMP) and for infections.
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Answer from: at Academic Institution
Data are limited but the combination of adalimumab and mycophenolate (or other immunosuppressive medications) appears to be safe and effective in various forms of sarcoidosis (Sweiss et al., PMID 24751453, Metyas et al., PMID 24576278, Miller et al., PMID 26828145, Villacis-Nunez & Thakral, PMID...
Answer from: at Academic Institution
What is the reason the patient needs a DMARD?