Hospital Medicine

Hemostasis/Thrombosis   

Questions discussed in this category



Considering the short half-life, at what point would it be deemed too late to administer any reversal agent, and to consider withholding it?

High-risk PEs are typically treated with loading doses of anticoagulants or bridging with LMWH. Do you omit the bridging/loading period and go straigh...

Do you increase rivaroxaban to 10 mg daily during the inpatient stay, or do you prefer to add LMWH or SC heparin?

If they have been on IV heparin for 3 days, for example, would you subtract those days from the recommended loading dose time?

Assume thrombolytics are not indicated. Do you favor early DOAC transition after 24-48 hours of heparin gtt or do you favor LMWH for 10-14 days follow...

Is it different than early mobility that we always encourage?

What is your preferred agent (DOAC, warfarin, enoxaparin), and is periprocedural bridging necessary?

How does cirrhosis and/or underlying thrombophilia affect your decision?

The use of anti-fibrinolytics is typically contraindicated in DIC, but does it have benefit in DIC states characterized by hyperfibrinolysis?

Does having a concurrent consumptive process e.g. DIC change your management? 


Papers discussed in this category


Lancet, 2016 May 10

J Vasc Interv Radiol, 2020 Sep 09

Lancet (London, England), 2010-07-03

J Intensive Care, 2014 Feb 20

The New England journal of medicine, 2019-01-24

N Engl J Med, 2022 Dec 22

Hematology. American Society of Hematology. Education Program, 2015

Journal of hospital medicine, 2019-01

The New England journal of medicine, 2019 Feb 18

Phlebology, 2020 Mar 02

VASA. Zeitschrift fur Gefasskrankheiten, 2001 Jul

Journal of vascular surgery, 2000 Nov

The Lancet. Haematology, 2021 Aug 04

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2023 Jan-Dec

Blood advances, 2018-11-27

Stroke, 2015 Oct 29

Research and practice in thrombosis and haemostasis, 2023 May 20