Infectious Disease

HIV & AIDS

Questions discussed in this category

What is your approach when cryptococcus serum or CSF antigen titers do not change despite treatment in HIV-positive patients with cryptococcal meningitis or invasive disease, but there is clinical improvement and cultures remain negative?

1 Answer available

How do you approach management for patient's with HIV on ART with persistent low level viremia but no new resistance mutations identified?

1 Answer available

What is your approach to a positive PPD or IGRA in a patient with well-controlled HIV without significant TB risk factors?

3 Answers available

What are your top takeaways from ID Week 2024?

1 Answer available

What steps do you recommend to ensure continued viral suppression and prevent drug resistance in an HIV patient on injectable cabotegravir and rilpivirine who misses their scheduled injection appointment by two weeks?

1 Answer available

How would you manage a patient with well controlled HIV on Biktarvy, who is interested in switching to injectable HAART but also has a history of a prior Hepatitis B Infection?

2 Answers available

Is there a role for routine LP in HIV patients with disseminated histoplasmosis even in the absence of CNS signs/symptoms?

Extrapolating from standard practice for management of cryptococcal antigenemia?

1 Answer available

Would you recommend starting a moderate-intensity statin in a patient under the age of 40 years old with HIV and a 10-year ASCVD risk estimate below 5%?

The REPRIEVE trial included participants who were between 40 and 75 years old.

1 Answer available

When would you add a third antibacterial agent in addition to macrolide and ethambutol for treatment of a patient with HIV and disseminated MAC?

1 Answer available

In clinical practice, are you using single-dose liposomal amphotericin B for treatment of cryptococcal meningitis for patients living with HIV?

1 Answer available

How do you counsel HIV patients with an undetectable viral load on breastfeeding?

2 Answers available

How do you apply the CDC PrEP guidelines for cisgender women, particularly when faced with underreported risk behaviors or uncertain partner HIV status?

1 Answer available

What is your approach to anal pap screening among MSM with HIV, and if routinely recommend, starting at what age (assuming access to HRA)?

1 Answer available

For patients on PrEP, is there a role for HIV RNA PCR screening in addition to 4th generation antigen/antibody testing?

1 Answer available

What is your approach to starting antiretroviral therapy in a patient living with HIV who is diagnosed with cryptococcal meningitis?

1 Answer available

Do you treat patients with HIV-AIDS and positive cryptococcal antigenemia but negative CSF cryptococcal antigen with standard meningitis treatment given the potential for the postzone effect?

1 Answer available

Given recent data from the REPRIEVE trial, how will you adapt your practice with regards to prescribing statins to patients living with HIV?

1 Answer available

How do you approach a well controlled HIV patient with diffuse cutaneous kaposi sarcoma who failed to respond to radiation, paclitaxel and monthly liposomal doxorubicin?

1 Answer available

Do you rule out TB in patients with AIDS and lobar pneumonia?

What’s your threshold to get the three AFBs and place the patient in airborne isolation?

1 Answer available

Papers discussed in this category

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019-01-18

Short-course High-dose Liposomal Amphotericin B for Human Immunodeficiency Virus-associated Cryptococcal Meningitis: A Phase 2 Randomized Controlled Trial.

The New England journal of medicine, 2022 Mar 24

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.

The Cochrane database of systematic reviews, 2018 Jul 24

Early versus delayed antiretroviral treatment in HIV-positive people with cryptococcal meningitis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023 Jul 05

Early Antiretroviral Therapy Not Associated With Higher Cryptococcal Meningitis Mortality in People With Human Immunodeficiency Virus in High-Income Countries: An International Collaborative Cohort Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-12

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study.

The Lancet. Oncology, 2022 Mar 10

PD-1 blockade with pembrolizumab in classic or endemic Kaposi's sarcoma: a multicentre, single-arm, phase 2 study.

The New England journal of medicine, 1987-03-05

Accelerated loss of antibody to hepatitis B surface antigen among immunodeficient homosexual men infected with HIV.

Hepatology (Baltimore, Md.), 2018 Apr

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Dec 31

Global Burden of Hepatitis B Infection in People Living With Human Immunodeficiency Virus: A Systematic Review and Meta-analysis.

Journal of viral hepatitis, 2019 Dec 22

Prevalence and burden of HBV co-infection among people living with HIV: A global systematic review and meta-analysis.

Topics in antiviral medicine, 2023 Mar 31

Chronic hepatitis B and HIV coinfection.

Journal of acquired immune deficiency syndromes (1999), 2023 Oct 01

Brief Report: Hepatitis B Infection or Reactivation After Switch to 2-Drug Antiretroviral Therapy: A Case Series, Literature Review, and Management Discussion.

The Journal of infectious diseases, 2007-12-15

Decreased adherence to antiretroviral therapy observed prior to transient human immunodeficiency virus type 1 viremia.

AIDS (London, England), 2021 Nov 01

HIV-1 viral blips are associated with repeated and increasingly high levels of cell-associated HIV-1 RNA transcriptional activity.

Current HIV/AIDS reports, 2023 Nov 13

Learning from Persistent Viremia: Mechanisms and Implications for Clinical Care and HIV-1 Cure.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994-05

Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis.

HIV clinical trials, 2000

Clinical utility of monitoring serum cryptococcal antigen (sCRAG) titers in patients with AIDS-related cryptococcal disease.

Journal of clinical microbiology, 2005 Nov

The role of cryptococcal antigen assay in diagnosis and monitoring of cryptococcal meningitis.

Infectious Disease

HIV & AIDS

Questions discussed in this category

Papers discussed in this category

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