Infectious Disease

Syphilis

Questions discussed in this category

How have you adjusted your practice for treatment of syphilis in light of the penicillin G benzathine shortage?

Do you consider late latent syphilis adequately treated if a patient receives a 10-14 day course of IV ceftriaxone for another indication?

Or would you still offer penicillin G benzathine once weekly concurrently?

1 Answer available

Does a low serofast RPR titer (such as 1:1 or 1:2) in the setting of a remote history of appropriately treated latent syphilis in a patient with now uveitis of yet unknown etiology referred from ophthalmology for possible ocular syphilis make a diagnosis of ocular syphilis less likely?

What is your approach to guiding ophthalmologists regarding our clinical suspicion for ocular syphilis and does the quantification of the titer help i...

1 Answer available

What is the preferred treatment regimen for cardiovascular syphilis, specifically syphilitic ostial coronary artery disease?

1 Answer available

After a course of treatment for neurosyphilis, do you administer an additional IM dose of penicillin G one week after finishing the course of IV penicillin therapy?

1 Answer available

Papers discussed in this category

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 2021 Jul 23

Sexually Transmitted Infections Treatment Guidelines, 2021.

Journal of ophthalmic inflammation and infection, 2015-12

Clinical and laboratory characteristics of ocular syphilis: a new face in the era of HIV co-infection.

JAMA ophthalmology, 2024 Jan 01

Rising Incidence of Syphilitic Uveitis-Related Hospitalizations in the US.

Investigative ophthalmology & visual science, 2016 Feb

Clinical Manifestations and Outcome of Syphilitic Uveitis.

The American journal of medicine, 1992-11

Response of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with human immunodeficiency virus.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017 Oct 30

A Multicenter Study Evaluating Ceftriaxone and Benzathine Penicillin G as Treatment Agents for Early Syphilis in Jiangsu, China.

Open forum infectious diseases, 2024 Mar 13

Syphilis Treatment: Systematic Review and Meta-Analysis Investigating Nonpenicillin Therapeutic Strategies.

Infectious Disease

Syphilis

Questions discussed in this category

Papers discussed in this category

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