Internal Medicine

IgG4-Related Disease

Questions discussed in this category

How would you manage a patient with highly active ankylosing spondylitis, iritis and Crohn’s, controlled with weekly adalimumab with co-morbid IgG4RD and intolerance of azathioprine due to elevated LFTs?

IgG4 manifestations include autoimmune pancreatitis and periaortic soft tissue mass.

2 Answers available

How would you manage autoimmune pancreatitis in a patient after Whipple's procedure?

1 Answer available

What is your treatment algorithm for management of retroperitoneal fibrosis that does not respond to high-dose glucocorticoids?

1 Answer available

When would you consider rituximab as induction therapy in IgG4-related disease?

4 Answers available

Would you intensify therapy in IgG4 related disease based solely on a persistently significantly elevated IgG4 level when all disease manifestations and inflammatory markers have normalized?

1 Answer available

How do you approach a patient with IgG4-related disease who has failed rituximab and mycophenolate and continues to rely on high-dose steroids?

The case I am considering involves a patient with biopsy-proven fibrosing dacryoadenitis.

1 Answer available

Papers discussed in this category

Annals of the rheumatic diseases, 2015-06

Rituximab for IgG4-related disease: a prospective, open-label trial.

Neth J Med,

The treatment outcomes in IgG4-related disease.

Medicine (Baltimore),

Therapeutic approach to IgG4-related disease: A systematic review.

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