Internal Medicine

Obstructive Lung Disease

Questions discussed in this category

What is the rationale/evidence to support doing 4 puffs of albuterol vs. 2 puffs for a reversibility study?

3 Answers available

Have you observed adverse mental health side effects in patients who start montelukast?

In light of the FDA warning about mental health side effects of the medication have you observed in particular any patients develop suicidal thoughts ...

1 Answer available

How do you approach the use of benzodiazepines in patients with chronic medical illnesses that may be susceptible to respiratory compromise (e.g., CHF, COPD, ILD)?

Should you work to wean patients of benzodiazepines? Is your approach different for patients who have been on benzodiazepines for years? What would yo...

3 Answers available

Do you feel high dose Symbicort or Dulera is appropriate to use for SMART despite these doses not being studied in clinical trials?

1 Answer available

When would you recommend prescribing an asthmatic patient budesonide/salbutamol rather than budesonide/formoterol?

2 Answers available

Is methacholine challenge on its way out?

1 Answer available

Is there a role for biologics to improve lung function in patients who have severe asthma with daily symptoms and reduced lung function but do not experience frequent exacerbations?

2 Answers available

How do you factor smoking history into biologic selection for asthma since the clinical trials generally excluded these patients?

1 Answer available

What factors do you consider prior to offering a trial of ICS/LABA therapy versus a methacholine challenge test in patients with suspected asthma but normal pulmonary function testing?

1 Answer available

Do you diagnose obstruction by the criteria of FEV1/FVC < 70% or < LLN?

5 Answers available

What is your approach to inhaler therapy in a patient with asthma who cannot be on an inhaled corticosteroid due to ocular disease?

1 Answer available

What is your threshold to start triple therapy in mild to moderate asthma/COPD overlap with minimal functional limitation?

1 Answer available

Is there a role for biologics to help patients with ABPA who are steroid responsive and have removed their allergen insult, but continue to have an elevated serum IgE and incomplete resolution of symptoms return to their baseline functional status?

1 Answer available

Is there a role for the use of biologics as steroid sparing agents in treating patients with ABPA who are intolerant to prednisone?

1 Answer available

Do you use continuous or intermittent bronchodilator therapy in severe airway obstruction?

1 Answer available

What is your second line therapy for patients with EGPA with mainly pulmonary and sinonasal features who did not respond to mepolizumab 300 mg/month and still require high doses of steroid?

2 Answers available

Is there a role for biologic therapies in asthma-COPD overlap syndrome with evidence of type 2 inflammation?

2 Answers available

Papers discussed in this category

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000-04

Practice guidelines for diseases caused by Aspergillus. Infectious Diseases Society of America.

Chest, 2018 Jan 11

A Randomized Trial of Itraconazole vs Prednisolone in Acute-Stage Allergic Bronchopulmonary Aspergillosis Complicating Asthma.

J Allergy Clin Immunol Pract, 2021 Mar 06

Real-World Effectiveness of Anti-IL-5/5R Therapy in Severe Atopic Eosinophilic Asthma with Fungal Sensitization.

Chest, 2020 Aug 31

Real-World Effectiveness of Benralizumab in Severe Eosinophilic Asthma.

J Allergy Clin Immunol Pract, 2020 Jun 16

Omalizumab Is an Effective Intervention in Severe Asthma with Fungal Sensitization.

Cureus, 2020 Aug 12

Mepolizumab as Possible Treatment for Allergic Bronchopulmonary Aspergillosis: A Review of Eight Cases.

J Allergy Clin Immunol Pract, 2015 Jan 29

Clinical efficacy and immunologic effects of omalizumab in allergic bronchopulmonary aspergillosis.

Journal of asthma and allergy, 2019

Two vs four puffs of albuterol: does dose change bronchodilator response?

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