Allergy & Immunology   

Is it common to have IgA deficiency in absence of any recurrent infections?

Are your results different in adults whereby a particular trigger is often found and very helpful versus in children?

Will either blocking IgE better or oral food desensitization be superior in increasing chances to outgrow a food allergy?

Seems like AAP and AAAI support switch to 0.3 woolen at 55lbs and FDA and Woolen package insert at 66lbs. Any thoughts on when to switch?

Do you start/trial them on another biologic or just rely on topical therapies?

Female in her early 40s with chronic spontaneous urticaria occurring consistently only at night for the past 4 years. Lesions develop only at night wh...

Is there utility when classic inflammatory markers (ESR,CRP) or disease specific markers (C3, C4, dsDNA) do not correlate with patients disease activi...

I have an elderly patient with a history of biopsy-proven psoriasis on IL-17 biologic therapy. She has developed an intense itch without a primary ras...

(preschool-aged patients)

Is a BM biopsy a must when there is skin involvement? If tryptase level is mildly elevated but less than 20 would you recommend a BM biopsy?

Anemia is secondary to menorrhagia. No gynecologic interventions were possible.

Patient became acutely flushed, developed severe and prolonged hypotension with brief loss of consciousness, dizziness, nausea, dry heaves and headach...

Are dilute bleach baths enough? Should they use any topical therapies? Is there a need for Staph decolonization with something like mupirocin?

If a deficiency is present, do you consider IVIG to treat non-infectious symptoms such as skin rash, arthritis or hematological abnormalities? 

Are there cases where food or environmental allergies significantly worsen eczema in children?

Especially in the setting of these being more narrow acting than tofacitinib, should we consider them safer than our old drugs?

Specifically, how do you treat the delayed headache, not the headache that develops during the infusion where pre-hydration and slowing down the rate ...

If all work-up including peripheral flow, bone marrow biopsy, PET-CT returns negative, what additional management (if any) would be recommended?

Are there major differences in standard conditioning and/or GVHD prophylaxis regimens utilized? Does the non-relapse mortality different significantl...

E.g., inflammatory polyarthritis or inflammatory myopathy with onset within 2 weeks of documented COVID infection

For example, healthcare workers who require these vaccines for employment