Medical Oncology

Germ Cell Tumors

Questions discussed in this category

How would manage a patient with primary mediastinal NSGCT who has radiographic response but rising AFP while receiving VIP?

Do you routinely check tumor markers between cycles when managing NSGCT?

1 Answer available

How do you decide between RPLND vs. chemotherapy in patients with Stage IIA mixed germ cell tumor as primary treatment?

3 Answers available

Which chemo regimen, if any, would you use as adjuvant treatment in a young patient with primary malignant thyroid teratoma?

Would surgical margins, evidence of angiolymphatic spread, number of lymph nodes removed during surgery inform your decision?

1 Answer available

How would you approach therapy for a patient with non-seminomatous germ cell tumor, cT3N3Mx and symptomatic lower extremity thrombus extending to the IVC when it is unclear if bland or tumor thrombus?

HCG 850, AFP normal, LDH ~500 pre-orchiectomy. If tumor thrombus, would you favor 4c of BEP? Would you try biopsy it? How common is IVC thrombu...

1 Answer available

What treatment regimen would you recommend for young adults with platinum refractory relapsed germ cell tumors?

2 Answers available

How do you approach a patient with multiply relapsed germ cell tumor with rising tumor markers but no obvious site of disease?

If standard of care BEP chemo, tandem transplant, and radiation to primary site have been done previously.

1 Answer available

Papers discussed in this category

Ann Oncol, 2007 Nov 15

Combination chemotherapy with gemcitabine, oxaliplatin, and paclitaxel in patients with cisplatin-refractory or multiply relapsed germ-cell tumors: a study of the German Testicular Cancer Study Group.

J Clin Oncol, 2019 Jun 10

Management of Stage II Germ Cell Tumors: Be Sure, Be Patient, Be Safe.

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