Questions discussed in this category
How does time since radiation, original PSA and grade group/gleason score inform your decision?
FDG PET, Axumin PET, Bone scan? Or just proceed with salvage ADT/RT?
How do you decide between ureteral stent and percutaneous nephrostomy for decompression?
Which patients specifically benefit from both mpMRI and PET-PSMA?
Has this recent retrospective analysis published in Lancet Oncology changed your practice?
Will you use it rather than a carboplatin-containing regimen?
Based on GI regimen or urothelial carcinoma regimens?
How would you treat such a patient?
Confirmed no urothelial carcinoma and muscle in specimen without involvement.
Does this raise concerns about the efficacy of adjuvant immune checkpoint inhibition? Are any preliminary results from AMBASSADOR (adjuvant pembrolizu...
The forest plot from CheckMate 274 did not show a benefit for such patients?
How would you select between adjuvant chemotherapy and adjuvant nivoluma...
Is a 3 month delay too long in someone who had postoperative complications?
Are there other high or very high risk features that would also contribute to your decision making?
GS 4+4. PSA low (1-2). CT and bone scan negative for lymphadenopathy or metastatic disease. Prostate MRI pending.
What neoadjuvant or adjuvant therapy would you give?
Should cystectomy remain standard of care?
(Recently debated in JAMA Oncology:
http://jamanetwork.com/journals/jamaoncology/article-abstract/2520055...
Is there a role for salvage LN dissection or salvage RT to the node? And is there a role for systemic therapy (ADT or chemotherapy) in addition? If yo...
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Papers discussed in this category
The New England journal of medicine, 2015-08-20
Clinical genitourinary cancer, 2018-12
J Urol, 2020 Apr
Lancet, 2020 Mar 05
Urology, 2000-11-01
Abdom Radiol (NY), 2019 Aug 29
Lancet Oncol, 2021 May 26
N Engl J Med,
Lancet Oncol, 2021 Mar 12
N. Engl. J. Med., 2012-04-19
European urology, 2017-07
Urol Oncol, 2022 Mar 27
J Urol, 2019 01
Nat Rev Urol, 2021 Jan 11
N Engl J Med, 2020 Sep 18
J Clin Oncol, 2022 Aug 30
J Urol, 2021 Jan 27
Eur Urol, 2020 Jan 08
Lancet, 2016 Mar 19
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-07-10
The Lancet. Oncology, 2023 May 12
International journal of radiation oncology, biology, physics, 2023 Jul 28
BJU international, 2017 May 29
European urology, 2022 Apr 18
The New England journal of medicine, 2018-05-10
The New England journal of medicine, 2020 Mar 05
J Clin Oncol, 2021 Jan 20
JAMA oncology, 2023 Mar 01
Int J Radiat Oncol Biol Phys, 2000 Sep 01
Pract Radiat Oncol, 2023 Jul 11
International journal of radiation oncology, biology, physics, 2024 Feb 28
Eur Urol, 2020 Dec 10