Neurology

Breast Cancer, Non-metastatic

Questions discussed in this category

What recommendations would you make for a patient on long-term phenytoin due to epilepsy with a newly diagnosed breast cancer requiring doxorubicin as part of her chemotherapy?

How would you counsel the patient given the drug interactions present?

1 Answer available

How would you manage a patient who develops acute stroke during neoadjuvant chemotherapy with KEYNOTE-522 for Stage III triple negative breast cancer?

Would you continue KEYNOTE-522 neoadjuvant therapy? The patient has a PMH of sarcoidosis with no stroke risk factors. No residual deficits.

1 Answer available

How do you modify TNBC neoadjuvant chemotherapy in patients with multiple sclerosis?

1 Answer available

How would you manage adjuvant endocrine therapy for a postmenopausal patient with early stage HR+ breast CA who develops an ischemic CVA on an AI?

Presuming that work-up for cardioembolic sources is negative, how would you proceed?

1 Answer available

Papers discussed in this category

Circulation, 2020 Feb 17

Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study.

N. Engl. J. Med.,

Pembrolizumab for Early Triple-Negative Breast Cancer.

PloS one, 2017

Risk of thromboembolism in cisplatin versus carboplatin-treated patients with lung cancer.

Circulation, 2016-03-29

Vascular Toxicities of Cancer Therapies: The Old and the New--An Evolving Avenue.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991 Feb

Venous and arterial thrombosis in patients who received adjuvant therapy for breast cancer.

Journal of stroke, 2020 Jan 31

Cancer-Related Stroke: An Emerging Subtype of Ischemic Stroke with Unique Pathomechanisms.

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