Ophthalmology

Neuro-Ophthalmology

Questions discussed in this category

What criteria do you use to decide the duration of IV steroids in patients with optic neuritis?

Is it necessary to do a taper afterward and what would be the recommended tapering schedule/duration?

1 Answer available

How do you determine when to wean patients with idiopathic intracranial hypertension (IIH) off of acetazolamide?

3 Answers available

When do you use GLP-1 receptor agonists for the management of patients with idiopathic intracranial hypertension (IIH)?

1 Answer available

What would you recommend for long term management of extensive dural venous sinus thrombosis (CVST) in young females when the only provoking risk factor is combined OCP?

Thrombophilia testing, including JAK2 is negative. When would you stop anticoagulation?

4 Answers available

How do you utilize Diamox in patients with cerebral venous sinus thrombosis and vision symptoms who do not undergo thrombectomy/recanalization?

3 Answers available

What baseline visual testing, if any, do you recommend at diagnosis for patients with multiple sclerosis who deny visual complaints?

1 Answer available

What is your approach to the diagnosis and management of optic chiasmitis in systemic lupus erythematosus?

And have you ever seen it occur in isolation without any other manifestations of SLE?

1 Answer available

What is your approach to the treatment of visual snow syndrome?

1 Answer available

Is there any benefit from oral vs topical steroids in herpes zoster opthalmicus?

Would the management change if there were complications with optic neuritis?

1 Answer available

How do you use optical coherence tomography in the diagnosis and management of patients with multiple sclerosis and related diseases?

2 Answers available

Is thyrotropin receptor antibody a good biomarker to predict development of thyroid eye disease?

1 Answer available

Do you routinely obtain baseline vascular imaging (CTA, MRA, PET) in patients with suspected GCA, but negative temporal artery biopsy?

Per 2021 GCA Vasculitis Guidelines: low evidence, but conditional recommendation for CTA neck, chest, abd/pelvis. Is anybody following this or do you ...

2 Answers available

How do you manage a patient with giant cell arteritis treated with weekly tocilizumab and low dose glucocorticoid who develops sudden vision loss?

2 Answers available

How do you evaluate asymptomatic patients referred for benign intracranial hypertension?

If patients are asymptomatic, what work up do you typically proceed with?

3 Answers available

How do you decide on a steroid sparing agent for idiopathic orbital inflammation partially responsive to steroids?

1 Answer available

Can giant cell arteritis present with a partial cranial neuropathy?

3 Answers available

Do you generally recommend low dose aspirin for patients with giant cell arteritis?

2 Answers available

Would you recommend medical therapy for asymptomatic idiopathic intracranial hypertension with completely normal visual field testing?

2 Answers available

How do you approach the management of patients with one clinical demyelinating event and MOG+ antibody status?

Do you wait for a second clinical event or start immunomodulatory therapy right away?

3 Answers available

How do you approach the management of acute attacks of MOGAD-associated optic neuritis?

Specifically, what do you do if there is minimal improvement with IV steroids and/or IVIG?

2 Answers available

What is your approach to evaluation of underlying autoimmune disease in patients with bilateral scleromalacia?

1 Answer available

Which method do you prefer to assess for stigmata of old optic neuropathy?

Ex. optical coherence tomography, visual-evoked potentials

1 Answer available

What is your steroid-sparing agent of choice to treat GCA given the current tocilizumab shortage?

Thoughts on sarilumab vs methotrexate, or just treat with steroids alone

1 Answer available

How long do you continue steroid-sparing agents such as tocilizumab for GCA once the disease is in remission off steroids?

1 Answer available

At what point in GCA management do you typically introduce tocilizumab?

2 Answers available

How would you approach a symptomatic patient with with a history of whole brain RT with new bilateral MRI enhancing lesions within the optic nerves?

Would you suspect progressive disease v. radiation necrosis vs optic neuritis due to immunotherapy. Eyes were within radiation field 8 months ago.&nbs...

1 Answer available

Papers discussed in this category

Ann Intern Med, 2020 Sep 22

Risk for Serious Infection With Low-Dose Glucocorticoids in Patients With Rheumatoid Arthritis : A Cohort Study.

N Engl J Med,

Trial of Tocilizumab in Giant-Cell Arteritis.

Lancet, 2016 Mar 04

Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.

Mult Scler Relat Disord, 2020 Dec 16

Interleukin-6 inhibition with tocilizumab for relapsing MOG-IgG associated disorder (MOGAD): A case-series and review.

Neurology(R) neuroimmunology & neuroinflammation, 2017-07

Optical coherence tomography and visual evoked potentials in pediatric MS.

J Med Life,

Optical coherence tomography versus visual evoked potentials in detecting subclinical visual impairment in multiple sclerosis.

J Clin Neurol, 2018 Feb 28

Optical Coherence Tomography versus Visual Evoked Potentials for Detecting Visual Pathway Abnormalities in Patients with Neuromyelitis Optica Spectrum Disorder.

Mult Scler, 2014 Mar 03

Optical coherence tomography and visual evoked potentials: which is more sensitive in multiple sclerosis?

Mult Scler Relat Disord, 2016 Dec 23

Sensitivity of visual evoked potentials and spectral domain optical coherence tomography in early relapsing remitting multiple sclerosis.

Arthritis Rheum,

Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.

Arthritis Rheum,

Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis.

Arthritis Res Ther, 2021 Mar 22

Vision loss in patients with giant cell arteritis treated with tocilizumab.

JAMA Neurol,

The Dilemma of Diagnosing Idiopathic Intracranial Hypertension Without Papilledema in Patients With Chronic Migraine.

JAMA Neurol,

Prevalence of Incidentally Detected Signs of Intracranial Hypertension on Magnetic Resonance Imaging and Their Association With Papilledema.

Archives of ophthalmology (Chicago, Ill. : 1960), 2010-06

Diagnosis and grading of papilledema in patients with raised intracranial pressure using optical coherence tomography vs clinical expert assessment using a clinical staging scale.

European journal of neurology, 2013 Mar 29

Safety of lumbar puncture in patients with cerebral venous thrombosis.

Rheumatology (Oxford, England), 2015-03

Large-vessel giant cell arteritis: a cohort study.

Archives of ophthalmology (Chicago, Ill. : 1960), 2008 Jul

Treatment of acute optic neuritis: a summary of findings from the optic neuritis treatment trial.

The British journal of ophthalmology, 1997 Feb

Successful treatment of optic neuropathy in association with systemic lupus erythematosus using intravenous cyclophosphamide.

Stroke, 2023 Sep 07

Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anticoagulation With Rivaroxaban to Standard-of-Care in Symptomatic Cerebral Venous Thrombosis.

Stroke, 2024 Jan 29

Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement From the American Heart Association.

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