Pediatric Hematology/Oncology

Breast Cancer

Questions discussed in this category

How would you approach breast cancer screening in an adolescent patient with a CDH1 mutation?

1 Answer available

What are best practices for oncologists during the national platinum shortage?

Please specify how your institution is allocating resources now or will be soon.

13 Answers available

Do you routinely recommend loratadine for pegfilgrastim pain?

5 Answers available

When do you refer patients for germline testing when somatic tumor testing is negative for actionable mutations?

How reliable is somatic testing to detect an underlying germline predisposition?

2 Answers available

How would you counsel a young female patient who refuses to use contraception during radiotherapy?

Would your counseling change if she reported a history of unplanned pregnancy? Is there any wording or waiver you might be able to use warning her of ...

1 Answer available

Should special precautions be taken patients with Ehlers-Danlos syndrome receiving radiation therapy?

Would you have reservations in treating patients with breast, GI, or pelvic malignancies with radiation alone or concurrent chemoradiation?

2 Answers available

Should we be utilizing prophylactic G-CSF in our patients with intermediate risk of febrile neutropenia due to the COVID-19 pandemic?

Are you placing more weight on patient risk factors such as age >65 or co-morbidities?

2 Answers available

Papers discussed in this category

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016-07

Randomized phase II study of loratadine for the prevention of bone pain caused by pegfilgrastim.

Clinical breast cancer, 2003-02

Bone pain associated with once-per-cycle pegfilgrastim is similar to daily filgrastim in patients with breast cancer.

AJNR. American journal of neuroradiology, 1996-02

Induction and subsequent rupture of aneurysms of the circle of Willis after radiation therapy in Ehlers-Danlos syndrome: a plausible hypothesis.

Journal of the National Cancer Institute, 2016-06

An Ethical Framework for Allocating Scarce Life-Saving Chemotherapy and Supportive Care Drugs for Childhood Cancer.

Pediatrics, 2014 Feb 02

Chemotherapy drug shortages in pediatric oncology: a consensus statement.

N. Engl. J. Med.,

Pembrolizumab for Early Triple-Negative Breast Cancer.

The Journal of urology, 2018-12

Impact of the Number of Cycles of Platinum Based First Line Chemotherapy for Advanced Urothelial Carcinoma.

N. Engl. J. Med.,

Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer.

Lancet Oncol., 2014 Feb 18

Definitive chemoradiotherapy with FOLFOX versus fluorouracil and cisplatin in patients with oesophageal cancer (PRODIGE5/ACCORD17): final results of a randomised, phase 2/3 trial.

NEJM Evidence, 2022 Jun 1

Durvalumab plus Gemcitabine and Cisplatin in Advanced Biliary Tract Cancer

Br J Cancer, 2014 Apr 15

Gemcitabine-oxaliplatin plus prednisolone is active in patients with castration-resistant prostate cancer for whom docetaxel-based chemotherapy failed.

Cancer, 2011-06-15

Frontline treatment of localized osteosarcoma without methotrexate: results of the St. Jude Children's Research Hospital OS99 trial.

Eur J Cancer, 2017 Nov 28

Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study.

N. Engl. J. Med., 2019 Sep 28

Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer.

Lancet Oncol, 2021 Jan 18

First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial.

J Clin Oncol, 2021 Apr 19

Five-Year Outcomes With Pembrolizumab Versus Chemotherapy for Metastatic Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score ≥ 50.

J Clin Oncol, 2003 Jul 01

Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: a phase III trial of the Italian GEMVIN Investigators and the National Cancer Institute of Canada Clinical Trials Group.

Pediatric Hematology/Oncology

Breast Cancer

Questions discussed in this category

Papers discussed in this category

Related Topics in Pediatric Hematology/Oncology