Pediatric Hematology/Oncology

Ewing Sarcoma

Questions discussed in this category

When is a bone marrow biopsy indicated in the up-front evaluation of an AYA patient with Ewing sarcoma?

What is your local control approach to localized relapse of Ewing sarcoma in a site that was previously unresectable and received definitive radiation?

1 Answer available

For pediatric Ewing sarcoma, what is the role of metastatic site consolidation?

What volume and dose do you treat a bone met that has completely responded to chemo?

1 Answer available

What is the role of local control +/- whole lung irradiation in a patient with relapsed/refractory Ewing sarcoma to the hilum plus multiple lung nodules?

Patient initially achieved CR with VAC-IE with resolution of presumed lung mets and 100% necrosis in LLE primary tumor on BKA. Then was NED again afte...

2 Answers available

When do you evaluate or refer for a cancer predisposition syndrome in a young child diagnosed with a sarcoma?

3 Answers available

In light of the recent rEECur trial interim analysis, would you offer high-dose ifosfamide to an AYA patient with relapsed Ewing's sarcoma who initially had a complete response to up-front therapy?

J Clin Oncol 40, 2022 (suppl 17; abstr LBA2). https://meetings.asco.org/abstracts-presentations/209024

2 Answers available

How would you approach local control in a patient with extra-osseous metastatic Ewing sarcoma of the kidney?

1 Answer available

How would you treat refractory unresectable pulmonary metastases in high grade synovial sarcoma?

Patient received Pazopanib upfront with Ifos/Dox. Pulmonary metastatectomy is not an option as there are multiple mets.

2 Answers available

When should upfront molecular sequencing be performed in a pediatric or AYA patient with sarcoma?

1 Answer available

How do you manage patients with a history of severe ifosfamide neurotoxicity who need additional ifosfamide?

What is the role of methylene blue prophylaxis?

1 Answer available

Is there utility in metronomic chemotherapy in adolescent and young adult patients with refractory sarcoma?

2 Answers available

Would you offer immunotherapy for recurrent metastatic Ewing sarcoma if the tumor is MSI high or has high TMB?

2 Answers available

How would you modify Ewing sarcoma chemotherapy and timing of dialysis for a dialysis-dependent patient?

1 Answer available

Is there a maximum ifosfamide cumulative dose in patients with normal kidney function?

When offering ifosfamide / etoposide for relapsed osteosarcoma, patient is being given 2.8mg/m2 of ifosfamide. Is 6-8 cycles exceeding any known lifet...

1 Answer available

How do you incorporate high-dose chemotherapy with autologous stem cell rescue for a patient with relapsed, metastatic Ewing sarcoma?

2 Answers available

How do you approach myeloablative chemotherapy for high-risk Ewing sarcoma patients?

1 Answer available

Do you give post-operative radiation to Ewing sarcoma if there is poor histologic response to neoadjuvant therapy in a completely resected tumor?

1 Answer available

What treatment do you offer to a pediatric patient with metastatic ewing sarcoma who has completed VDC/IE chemotherapy?

1 Answer available

What systemic therapy do you recommend for a patient with a local relapse of ewing sarcoma who previously received VDC-IE?

Following local therapy, what is your choice of systemic therapy?

2 Answers available