Primary Care

Primary Immunodeficiency

Questions discussed in this category

When would you pursue genetic testing for severe recalcitrant atopic dermatitis?

1 Answer available

Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?

2 Answers available

What are the implications of checking post-vaccine titers after administration of Prevnar 20 compared to PPSV23?

1 Answer available

Do you give additional pneumococcal vaccines after a dose of PCV20 in patients with asplenia?

1 Answer available

Do you recommend lifelong antibiotic prophylaxis, or do you prefer a more selective approach based on risk factors in asplenic patients without a history of severe infections?

2 Answers available

What is the optimal timing for Zoster vaccine administration for a patient who recently recovered from herpes zoster infection and is now planning to start B-cell depletion therapy?

1 Answer available

How would you recommend dosing the MMR or other live vaccines for patients with rheumatoid arthritis on immunosuppressive medications such as anti-TNF alpha therapy?

For example, healthcare workers who require these vaccines for employment

1 Answer available

Do you recommend shingles vaccine to all immunosuppressed patients under the age of 50 y.o.?

1 Answer available

Papers discussed in this category

Ann Rheum Dis, 2019 Aug 14

2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases.

Lupus, 2014 Jul 30

Serious infections in systemic lupus erythematosus with a focus on pneumococcal infections.

MMWR. Morbidity and mortality weekly report, 2024 Sep 12

Use of 21-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024.

The Journal of allergy and clinical immunology, 2012-09

Use and interpretation of diagnostic vaccination in primary immunodeficiency: a working group report of the Basic and Clinical Immunology Interest Section of the American Academy of Allergy, Asthma & Immunology.

Immunology and allergy clinics of North America, 2020 Jun 09

Diagnosis and management of Specific Antibody Deficiency.

Journal of clinical immunology, 2019 Nov 08

Defining Polysaccharide Antibody Deficiency: Measurement of Anti-Pneumococcal Antibodies and Anti-Salmonella typhi Antibodies in a Cohort of Patients with Recurrent Infections.

Frontiers in immunology, 2021 Sep 30

Diagnostic Vaccination in Clinical Practice.

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