Rheumatology

Neuro-Ophthalmology

Questions discussed in this category

What is your approach to the diagnosis and management of optic chiasmitis in systemic lupus erythematosus?

And have you ever seen it occur in isolation without any other manifestations of SLE?

1 Answer available

How do you make the decision to empirically treat for GCA when a patient is referred but cannot be immediately seen in clinic?

When a PCP calls with concern for GCA and is wondering whether to start empiric steroids what data do you prioritize to make that decision and do you ...

4 Answers available

How would you interpret a temporal artery biopsy demonstrating focal chronic inflammation in the adventitia associated with small adventitial vessels and nerves without inflammation of the intima and media and without giant cells?

2 Answers available

Do you routinely obtain baseline vascular imaging (CTA, MRA, PET) in patients with suspected GCA, but negative temporal artery biopsy?

Per 2021 GCA Vasculitis Guidelines: low evidence, but conditional recommendation for CTA neck, chest, abd/pelvis. Is anybody following this or do you ...

2 Answers available

How do you manage a patient with giant cell arteritis treated with weekly tocilizumab and low dose glucocorticoid who develops sudden vision loss?

2 Answers available

How do you decide on a steroid sparing agent for idiopathic orbital inflammation partially responsive to steroids?

1 Answer available

Can giant cell arteritis present with a partial cranial neuropathy?

3 Answers available

Do you generally recommend low dose aspirin for patients with giant cell arteritis?

2 Answers available

Do you always perform temporal artery biopsy in patients with positive inflammatory markers and high clinical suspicion of GCA?

2 Answers available

Is either ESR or CRP more sensitive or specific for the diagnosis of GCA?

Additionally, what is the current role for temporal artery ultrasound in workup for GCA?

3 Answers available

What is your approach to evaluation of underlying autoimmune disease in patients with bilateral scleromalacia?

1 Answer available

What is your steroid-sparing agent of choice to treat GCA given the current tocilizumab shortage?

Thoughts on sarilumab vs methotrexate, or just treat with steroids alone

1 Answer available

How long do you continue steroid-sparing agents such as tocilizumab for GCA once the disease is in remission off steroids?

1 Answer available

At what point in GCA management do you typically introduce tocilizumab?

2 Answers available

Papers discussed in this category

Ann Intern Med, 2020 Sep 22

Risk for Serious Infection With Low-Dose Glucocorticoids in Patients With Rheumatoid Arthritis : A Cohort Study.

N Engl J Med,

Trial of Tocilizumab in Giant-Cell Arteritis.

Lancet, 2016 Mar 04

Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.

Arthritis Rheum,

Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.

Seminars in arthritis and rheumatism, 2012-06

Utility of erythrocyte sedimentation rate and C-reactive protein for the diagnosis of giant cell arteritis.

Arthritis Rheumatol, 2021 Jul 08

2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis.

Ann Rheum Dis, 2019 Jul 03

2018 Update of the EULAR recommendations for the management of large vessel vasculitis.

Mayo Clin Proc,

My Treatment Approach to Giant Cell Arteritis.

Arthritis Rheum,

Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis.

Arthritis Res Ther, 2021 Mar 22

Vision loss in patients with giant cell arteritis treated with tocilizumab.

Rheumatology (Oxford, England), 2015-03

Large-vessel giant cell arteritis: a cohort study.

Open access rheumatology : research and reviews, 2016

Polymyalgia rheumatica: observations of disease evolution without corticosteroid treatment.

Medicine, 2016 Feb

Description and Validation of Histological Patterns and Proposal of a Dynamic Model of Inflammatory Infiltration in Giant-cell Arteritis.

Histopathology, 2023 Aug 08

Age-related histopathological findings in temporal arteries.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 2023 Sep 06

Consensus statement on the processing, interpretation and reporting of temporal artery biopsy for arteritis.

BMC musculoskeletal disorders, 2016-08-24

The effect of clinical features and glucocorticoids on biopsy findings in giant cell arteritis.

The British journal of ophthalmology, 1997 Feb

Successful treatment of optic neuropathy in association with systemic lupus erythematosus using intravenous cyclophosphamide.

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