Drug induced lupus

Questions discussed in this category

How do you approach the continued use of TNF inhibitors in a patient with inflammatory arthritis who develops a positive dsDNA without clinical evidence of drug-induced lupus?

2 Answers available

Would you favor stopping hydralazine in a patient requiring it for refractory hypertension if they also have a high titer ANA in the absence of any SLE symptoms?

2 Answers available

How do you differentiate a lupus flare versus drug-induced lupus in patients with SLE on a drug associated with DILE?

2 Answers available

Is it ever reasonable to switch to a different TNFi as opposed to switching to an agent in a different class in a case of TNFi induced lupus or psoriasis?

In other words, do we think of TNFi induced lupus and TNFi induced psoriasis as a drug effect or a class effect?

1 Answer available

Papers discussed in this category

Seminars in arthritis and rheumatism, 2010-12

Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: clinical features and possible immunopathogenesis.

Clin Exp Rheumatol, 2012 Oct 17

Anti-tumour necrosis factor alpha therapy and increased risk of de novo psoriasis: is it really a paradoxical side effect?

Inflamm Bowel Dis,

Tumor necrosis factor α antagonist-associated psoriasis in inflammatory diseases: an analysis of the FDA adverse event reporting system.

Am J Clin Dermatol,

Tumor necrosis factor-alpha inhibitor-induced psoriasis or psoriasiform exanthemata: first 120 cases from the literature including a series of six new patients.

The Journal of rheumatology, 1992-02

Antibiotic allergy in systemic lupus erythematosus: a case-control study.

The British journal of dermatology, 2011-03

A systematic review of drug-induced subacute cutaneous lupus erythematosus.

Current opinion in rheumatology, 2018-09

Drug-induced lupus erythematosus: an update on drugs and mechanisms.

Lupus, 2014 Feb 20

Drug-induced lupus: Including anti-tumour necrosis factor and interferon induced.

Ann Rheum Dis, 2019 Feb 04

Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database.

Br J Dermatol, 2011 Jul 11

Drug-induced subacute cutaneous lupus erythematosus: evidence for differences from its idiopathic counterpart.

Mod Rheumatol, 2016 Feb 17

Safety and efficacy of upfront graded administration of trimethoprim-sulfamethoxazole in systemic lupus erythematosus: A retrospective cohort study.

Autoimmun Rev, 2012 Nov 30

Immunogenicity and autoimmunity during anti-TNF therapy.

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