Hematology

Gastroenterology

Questions discussed in this category

How do you counsel patients who experience diarrhea from mycophenolate mofetil (Cellcept)?

Do you generally recommend anti-diarrheals, dietary modifications, or consider this an unacceptable side effect and move to other therapies?

2 Answers available

How do you approach managing depression symptoms in patients who have had repeated high risk of bleeding?

When do you determine SSRI therapy is unsafe to pursue in such situations?

2 Answers available

When would you phlebotomize patients with secondary hemochromatosis, such as due to NAFLD/cirrhosis?

HFE gene mutations in C282Y and H63D are negative.

1 Answer available

How long do you anticoagulate for cirrhosis patients who have portal vein thrombosis extending to the mesenteric veins?

2 Answers available

What initial workup do you perform when there is a concern for porphyria?

1 Answer available

Should all patients diagnosed with B12 deficiency get a baseline EGD?

Should they be placed on routine EGD surveillance and if yes at what intervals?

1 Answer available

Do you discontinue or adjust azathioprine when a patient develops elevated MCV after starting it?

When it seems fairly certain that this is a drug effect is it something that can just be monitored or requires a change in approach?

2 Answers available

Is prophylactic anticoagulation indicated in patients with frequent ulcerative colitis flares?

If so, what agent(s) do you prefer?

1 Answer available

With what agents can you replace PPIs if they cause thrombocytopenia?

1 Answer available

Should platelet transfusions be considered for anti-platelet agent reversal in patients with major bleeding?

1 Answer available

Do you routinely start anticoagulation for a patient with newly diagnosed hepatocellular carcinoma presenting with a portal venous thrombosis?

3 Answers available

Papers discussed in this category

Blood, 2020 Sep 10

Anticoagulant therapy for splanchnic vein thrombosis: A systematic review and meta-analysis.

Blood Adv,

American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer.

J Pharm Pract, 2019 Mar 27

Lansoprazole-Induced Thrombocytopenia in a Critically Ill Patient: A Case Report.

Blood, 2014 Oct 15

How I treat splanchnic vein thrombosis.

Therapeutic drug monitoring, 2022 Jun 01

Drug-Drug Interactions Between Mycophenolic Acid and Proton Pump Inhibitors: A Systematic Review and Meta-Analysis.

Pharmacological research, 2016 Aug 10

Bleeding risk under selective serotonin reuptake inhibitor (SSRI) antidepressants: A meta-analysis of observational studies.

The Annals of pharmacotherapy, 2018 Aug 06

Clinical Management of Bleeding Risk With Antidepressants.

Am J Gastroenterol,

ACG Clinical Guideline: Hereditary Hemochromatosis.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 2016 Nov

Outcome of phlebotomy for treating nonalcoholic fatty liver disease: A systematic review and meta-analysis.

Journal of hepatology, 2022 Jun 01

EASL Clinical Practice Guidelines on haemochromatosis.

Hematology

Gastroenterology

Questions discussed in this category

Papers discussed in this category

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