Internal Medicine

Hemophilia   

Questions discussed in this category


Assume the patient has infrequent bleeding events every few years, with use of FIX replacement for acute bleeds only.

What type, dosage, and duration of treatment do you use? How does your practice change when there is an inhibitor?

Patient with high titer acquired FVIII inhibitor with no causative etiology.  Bleeding is well-controlled on emicizumab, but inhibitor has failed...

Have you used anticoagulants other than coumadin? Or is that the only appropriate agent given monitoring is based on PT/INR?

During the Stimate recall, how are we performing DDAVP challenges for newly diagnosed hemophilia A or von Willebrand disease?


Papers discussed in this category


Journal of thrombosis and haemostasis : JTH, 2013-04-10

J Thromb Haemost, 2009 Aug 19

Clin Appl Thromb Hemost, 2018 Jun 19

Haemophilia, 2020 Aug 3

Blood, 2012 Mar 12

Blood, 2016-07-14

Blood, 2016 Sep 26