Neurology

Dermatomyositis

Questions discussed in this category

Do you always biopsy patients who present with classic skin findings of dermatomyositis?

Should IVIG dosing in patients with autoimmune disease (i.e., dermatomyositis) who become pregnant continue to be based on actual weight at the time of each infusion, or should it be limited to pre-pregnancy weight?

2 Answers available

How do you approach sequentially tapering combination therapy (i.e., IVIG, mycophenolate, rituximab) for dermatomyositis that is in remission?

Would you taper the IVIG first or the cellcept/rituximab?

2 Answers available

How will you sequence therapies in dermatomyositis given the results of the ProDERM trial?

Will you still favor starting with steroids and traditional immunosuppressive agents, move IVIG earlier in your treatment strategy, or start with IVIG...

3 Answers available

Would you avoid combining JAK inhibitors with IVIG given the risk of thromboembolism?

4 Answers available

How do you recommend tapering IVIG in patients whose inflammatory myositis has achieved remission?

4 Answers available

Which myositis patients are good candidates for IVIG?

3 Answers available

How long can you treat dermatomyositis with IVIG?

3 Answers available

Papers discussed in this category

N Engl J Med, 2022 Oct 06

Trial of Intravenous Immune Globulin in Dermatomyositis.

The New England journal of medicine, 1993-12-30

A controlled trial of high-dose intravenous immune globulin infusions as treatment for dermatomyositis.

Medicine, 2021 Jan 08

Prospective, double-blind, randomized, placebo-controlled phase III study evaluating efficacy and safety of octagam 10% in patients with dermatomyositis ("ProDERM Study").

Curr Rheumatol Rep, 2023 Aug

Intravenous Immunoglobulin in Idiopathic Inflammatory Myopathies: a Practical Guide for Clinical Use.

NeoReviews, 2021 Jan

Update on the Use of Intravenous Immunoglobulin in Pregnancy.

Journal of clinical pharmacology, 2023 Jun

Physiologic Changes During Pregnancy and Impact on Small-Molecule Drugs, Biologic (Monoclonal Antibody) Disposition, and Response.

Neurology

Dermatomyositis

Questions discussed in this category

Papers discussed in this category

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