Hemostasis   

Assume the patient has infrequent bleeding events every few years, with use of FIX replacement for acute bleeds only.

Is there a factor XI goal that you target? Would you consider FVIIa products instead?

E.g. Normal F8, VWF activity ~50%, VWF antigen ~100%, ratio 0.5 sent in a patient with positive bleeding history Is there any clinical significance t...

Patient with high titer acquired FVIII inhibitor with no causative etiology.  Bleeding is well-controlled on emicizumab, but inhibitor has failed...

Have you used anticoagulants other than coumadin? Or is that the only appropriate agent given monitoring is based on PT/INR?