Pulmonology

Tuberculosis

Questions discussed in this category

What is the interpretation of two IGRAs with negative mitogen wells, in the absence of immunosuppression?

A patient on meloxicam for LBP developed high, persistent fevers and no other symptoms. An IGRA, among many tests, was sent. The IGRA’s mitogen ...

2 Answers available

Are there clinical scenarios in which you would start empiric treatment for pulmonary TB without microbiologic confirmation?

2 Answers available

How do you approach a patient on anti-TNF with positive Quantiferon (previously negative) with negative chest x-ray and no symptoms?

7 Answers available

How would you approach treatment of latent TB for patients who cannot tolerate rifamycins or isoniazid due to allergy, intolerance, or drug-drug interactions?

2 Answers available

For how long do you recommend treatment for latent tuberculosis prior to initiation of anti-TNF therapy?

6 Answers available

Does your institution have formal policies or work flows to reduce unnecessary IGRAs ordered for patients on biologics?

1 Answer available

How do you approach biologic initiation in patients with inflammatory arthritis and repeatedly indeterminate Quantiferon?

5 Answers available

Does your approach to treating latent tuberculosis differ in a patient on anti-fibrotic therapy?

1 Answer available

Do you rule out TB in patients with AIDS and lobar pneumonia?

What’s your threshold to get the three AFBs and place the patient in airborne isolation?

1 Answer available

Do you routinely monitor imaging or pulmonary function in patients with pulmonary TB after the completion of therapy?

1 Answer available

Do you routinely isolate and test for TB in a patient incidentally found to have a miliary pattern of nodules on chest CT?

2 Answers available

Papers discussed in this category

Scientific reports, 2017 Aug 10

Analysis of Factors Influencing Diagnostic Accuracy of T-SPOT.TB for Active Tuberculosis in Clinical Practice.

Ann Am Thorac Soc, 2017 May

Minimizing Tuberculosis Risk in Patients Receiving Anti-TNF Therapy.

Arthritis Care Res (Hoboken), 2016 Jan

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

Alimentary pharmacology & therapeutics, 2022 May 20

Review article: latent tuberculosis in patients with inflammatory bowel diseases receiving immunosuppression-risks, screening, diagnosis and management.

Infection control and hospital epidemiology, 2018-05

Time to Detection in Culture Supports Prediction of Low Transmissibility of Tuberculosis and Discontinuation of Isolation for Low-Risk Patients With A Single AFB-Negative and NAAT-Negative Respiratory Specimen.

Clinical microbiology reviews, 2018-10

Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection.

JAMA internal medicine, 2018-10-01

Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital.

American journal of respiratory and critical care medicine, 2021 Jan 15

The Epidemiological Importance of Subclinical Tuberculosis. A Critical Reappraisal.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024 Apr 18

NTCA Guidelines for Respiratory Isolation and Restrictions to Reduce Transmission of Pulmonary Tuberculosis in Community Settings.

American journal of respiratory and critical care medicine, 2019 Nov 15

Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline.

Pulmonology

Tuberculosis

Questions discussed in this category

Papers discussed in this category

Related Topics in Pulmonology