Rheumatology

General Hepatology

Questions discussed in this category

Is there a role for the use of transient elastography (FibroScan) to monitor liver fibrosis in patients on long term methotrexate?

3 Answers available

Is there a risk of hepatitis C activation with rituximab in a patient who has a history of HCV treated with antivirals and who is in sustained viral response?

1 Answer available

How do you monitor patients with incidentally found high titer anti-smooth muscle antibodies without stigmata of liver disease?

3 Answers available

How would you manage a patient with highly active ankylosing spondylitis, iritis and Crohn’s, controlled with weekly adalimumab with co-morbid IgG4RD and intolerance of azathioprine due to elevated LFTs?

IgG4 manifestations include autoimmune pancreatitis and periaortic soft tissue mass.

2 Answers available

How do you approach an obese patient on long-term methotrexate with normal liver tests in terms of workup for underlying fatty liver?

Would you start with a baseline ultrasound and then pursue further workup such as fibroscan if fatty liver is present, or other?

1 Answer available

Does hepatitis B vaccination reduce the risk of HBV reactivation associated with immunosuppressive therapy?

For example, in patients who are HbSAg negative, anti-HBc positive and HbSAb negative, does vaccination reduce reactivation risk?

2 Answers available

What is your approach to management of elevated liver enzymes in patients who recently started treatment with tocilizumab?

1 Answer available

How would you approach asymptomatic hepatic sarcoid?

Multiple lesions on PET

1 Answer available

How would you treat a poorly controlled seronegative RA patient who is steroid dependent and is on azathioprine for autoimmune hepatitis?

2 Answers available

How do you assess transaminitis in a patient with sarcoidosis with known liver involvement being treated with methotrexate?

1 Answer available

How do you manage patients who are Hepatitis B core antibody positive/surface antigen negative and starting a biologic DMARD (other than rituximab)?

1 Answer available

Papers discussed in this category

Arthritis Rheumatol, 2016 Jan

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

Arthritis and rheumatism, 1992-08

Comparison of azathioprine, methotrexate, and the combination of both in the treatment of rheumatoid arthritis. A controlled clinical trial.

Arthritis and rheumatism, 1995-12

Comparison of azathioprine, methotrexate, and the combination of the two in the treatment of rheumatoid arthritis. A forty-eight-week controlled clinical trial with radiologic outcome assessment.

Seminars in respiratory and critical care medicine, 2002-12

Hepatic, splenic, and gastrointestinal involvement with sarcoidosis.

Clinics in liver disease, 2019-05

Sarcoidosis and the Liver.

Eur J Gastroenterol Hepatol,

Natural history of hepatic sarcoidosis and its response to treatment.

Neth J Med,

Sarcoidosis of the liver: to treat or not to treat?

Semin Respir Crit Care Med, 2020 Aug 10

Hepatic Sarcoidosis: Current Concepts and Treatments.

Medizinische Klinik (Munich, Germany : 1983), 2002-11-15

[Prevalence of circulating autoantibodies in healthy individuals].

Journal for scientific research. Medical sciences, 2001 Apr

Occurence of autoantibodies in healthy Omani individuals.

Rheumatology

General Hepatology

Questions discussed in this category

Papers discussed in this category

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