Rheumatology

IVIG

Questions discussed in this category

Should IVIg dosing in patients with autoimmune disease (i.e., dermatomyositis) who become pregnant continue to be based on actual weight at the time of each infusion, or should it be limited to pre-pregnancy weight?

2 Answers available

Does IVIG or subcutaneous Ig interfere with monoclonal antibody therapy (i.e. dupilumab, infliximab, rituximab, etc)?

How should IVIG and either biologic injections or infusions be spaced?

2 Answers available

How do you recommend tapering IVIG in patients whose inflammatory myositis has achieved remission?

4 Answers available

Which myositis patients are good candidates for IVIG?

3 Answers available

What is your approach to checking IgG levels post vaccination to detect common variable immunodeficiency in patients with systemic lupus?

If a deficiency is present, do you consider IVIG to treat non-infectious symptoms such as skin rash, arthritis or hematological abnormalities?

1 Answer available

How do you treat post-IVIG headache that is not responsive to Tylenol or NSAIDs?

Specifically, how do you treat the delayed headache, not the headache that develops during the infusion where pre-hydration and slowing down the rate ...

4 Answers available

How long do you wait for response to corticosteroids and conventional synthetic DMARDs before considering IVIG in patients with HMGCR antibody positive IMNM?

1 Answer available

How long do you continue IVIG for myositis patients in remission on that therapy?

1 Answer available

Would you consider starting IVIG as initial steroid-sparing agent instead of azathioprine/methotrexate in a patient with inflammatory myopathy, high Jo-1, weakness with severe dysphagia and without skin involvement or ILD?

1 Answer available

Papers discussed in this category

N Engl J Med, 2022 Oct 06

Trial of Intravenous Immune Globulin in Dermatomyositis.

Clinical pharmacokinetics, 2018-12

Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease.

Frontiers in immunology, 2018

Reversing Autoimmunity Combination of Rituximab and Intravenous Immunoglobulin.

Clinical immunology (Orlando, Fla.), 2020 Jul 15

The potential impact of timing of IVIG administration on the efficacy of rituximab for immune tolerance induction for patients with Pompe disease.

The Pediatric infectious disease journal, 2018 Oct

Infliximab Plus Intravenous Immunoglobulin (IVIG) Versus IVIG Alone as Initial Therapy in Children With Kawasaki Disease Presenting With Coronary Artery Lesions: Is Dual Therapy More Effective?

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017 Nov 03

Successful IVIG treatment without discontinuation of TNF-α blocker in Guillain-Barre syndrome induced by adalimumab in patient with Crohn's disease.

Semin Arthritis Rheum, 2007 Feb

Common variable immunodeficiency in systemic lupus erythematosus.

J Clin Rheumatol, 2021 Dec 01

Intravenous Immunoglobulin for Inflammatory Myositis: Experience in a Tertiary Medical Center.

Am J Med, 1984 Mar 30

Immunoglobulin G (IgG) subclasses and human disease.

Lupus, 2007

Selective IgA deficiency in children and adults with systemic lupus erythematosus.

Autoimmun Rev, 2022 Aug 24

Efficacy and safety of intravenous immunoglobulin in patients with lupus nephritis: A systematic review of the literature.

Medicine, 2021 Jan 08

Prospective, double-blind, randomized, placebo-controlled phase III study evaluating efficacy and safety of octagam 10% in patients with dermatomyositis ("ProDERM Study").

Curr Rheumatol Rep, 2023 Aug

Intravenous Immunoglobulin in Idiopathic Inflammatory Myopathies: a Practical Guide for Clinical Use.

NeoReviews, 2021 Jan

Update on the Use of Intravenous Immunoglobulin in Pregnancy.

Journal of clinical pharmacology, 2023 Jun

Physiologic Changes During Pregnancy and Impact on Small-Molecule Drugs, Biologic (Monoclonal Antibody) Disposition, and Response.

Rheumatology

IVIG

Questions discussed in this category

Papers discussed in this category

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