Questions discussed in this category
Would clinical stage or nodal status affect your decision?
For a node positive, triple negative patient that underwent neoadjuvant chemotherapy followed by breast conservation with a complete pathologic respon...
Young patient, germline BRCA carrier with cT1cN0 to ypT2N0 disease after docetaxel/ cyclophosphamide x 4.
Assume normal cardiac function and no obvious co-morbidities. No anthracycline previously due to age alone. The patient’s BRCA status is unknown...
Patient previously received neoadjuvant ddAC-T with residual disease at surgery, followed by adjuvant capecitabine which was completed 2 months prior ...
CNS recurrence occurred within two years of prior neoadjuvant therapy
If so, what would be the regimen that you would consider and what factors would sway you for or against chemotherapy for such patients?
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Papers discussed in this category
Eur. J. Cancer, 2017 Aug 04
N. Engl. J. Med.,
Journal of the National Comprehensive Cancer Network : JNCCN, 2017-10
N. Engl. J. Med.,
Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-12-01
N Engl J Med, 2021 Jun 03
Annals of surgical oncology, 2019 Jun 21
The New England journal of medicine, 2024 Sep 15
Nature medicine, 2024 Sep 13
Annals of oncology : official journal of the European Society for Medical Oncology, 2024 Oct 21
The New England journal of medicine, 2024 Sep 15
BMJ Open, 2019 Oct 15
J Clin Oncol, 2020 Jul 30
JAMA oncology, 2024 Oct 01
Lancet Oncol., 2019 Jan 30