How would you treat an elderly female with residual TNBC following surgery and neoadjuvant Carboplatin and Paclitaxel?

Assume normal cardiac function and no obvious co-morbidities. No anthracycline previously due to age alone. The patient’s BRCA status is unknown, but presumably negative given her age. She has not received Capecitabine yet at this time.

Answer from: Medical Oncologist at Academic Institution

I think there will be some differing opinions on this. There are a number of things I would factor in assuming the patient has enough life expectancy where the breast cancer is the main mortality risk. 1) Data from carbo/taxane neoadjuvant trials (Sharma et al CCR 2018) and others suggest RCB1 ...

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Medical Oncologist at Joliet Oncology - Hematology Associates, Ltd.
I thought CREATE-X did allow TC regimen.

Medical Oncologist at H Lee Moffitt Cancer Center, University of South Florida
CREATE-X did but the number of TC-treated patients...

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How would you treat an elderly female with residual TNBC following surgery and neoadjuvant Carboplatin and Paclitaxel?

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