Do you change your definitive therapy approach for a patient with locally advanced central NSCLC with obstruction of a mainstream bronchus and subsequent collapse of the lung?

In a stable patient, do you perform standard chemoRT in 2 Gy fractions with IMRT for urgently start with a few high dose fractions (ex 4Gy/fx) and bridge to a definitive CRT plan? How do you contour your lung volume with a collapsed lung?

Answer from: Radiation Oncologist at Academic Institution

Treating a patient with a collapsed lung with definitive CRT can be difficult. Those patients typically have a higher risk of infection and often have increases in the rates of symptomatic pneumonitis. My first priority is to try to get the lung open before initiating definitive treatmen...

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Do you change your definitive therapy approach for a patient with locally advanced central NSCLC with obstruction of a mainstream bronchus and subsequent collapse of the lung?

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