Do you consider multifocal disease an indication for chemotherapy with trastuzumab in patients with microinvasive Her2+/HR- breast cancer?
Answer from: Medical Oncologist at Academic Institution
Not necessarily those with just 2 or 3 foci of microinvasive disease, but I am concerned when a patient has multiple (though I'm not sure if the number is 4 or 7 or 10) foci of microinvasion within a sizable area of high-grade, ER- DCIS, especially when the pathologist says that there are too m...