Do you consider treatment of the supraclavicular region mandatory for breast cancer patients with a chest wall recurrence?  

In our practice at MD Anderson, we routinely treat the chest wall and undissected nodal basins in patients with chest wall recurrences who have not had prior radiation. As most of these patients have undergone prior axillary surgery, it is plausible that they will have aberrant lymphatic drainage. T...

The question of treatment to regional nodes in isolated chest wall recurrences for breast cancer patients is a good one. At least two older retrospective series come to mind, both supporting the role for chestwall + regional nodal RT (Toonkel et al., The significance of local recurrence of carcino...