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Do you ever recommend concurrent chemotherapy for high risk squamous cell skin cancer radiation?
What dose of radiation, what type of chemo, and what indications?
Answer from: Radiation Oncologist at Academic Institution
Yes.
The dose of radiation depends on the treatment scenario (adjuvant vs definitive). I generally follow NCCN guidelines, and give the same dose whether or not chemo is given. For bulky tumors, I might use a higher radiation dose if no chemotherapy is given. In general, the radiation dose is...
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Answer from: Radiation Oncologist at Community Practice
We generally do not add platinum concurrent chemotherapy to radiotherapy for high-risk cutaneous squamous cell carcinoma off trial. Most patients are treated postoperatively. The TROG 05.01 randomized trial reported no significant difference in locoregional control, metastasis, or survival by adding...