Do you extend the duration of maintenance therapy past 24 months for patients with ANCA glomerulonephritis who have multiple organ involvement?  

The duration of maintenance therapy in patients with AAV depends on many factors and should be individualized. Some factors that are associated with a higher risk of relapse include PR3 positivity, seroconversion from negative to positive, ENT disease, use of a tailored approach to RTX dosing, and u...

When deciding on the duration of maintenance therapy, the risk of relapse, patient characteristics, and the extent of underlying organ damage will factor into the decision. In patients with a higher risk of relapse including PR3 Positive (especially if persistently positive), patients with lung/ENT...